eF-site ID 1ci7-B PDB Code 1ci7 Chain B click to enlarge Title TERNARY COMPLEX OF THYMIDYLATE SYNTHASE FROM PNEUMOCYSTIS CARINII Classification TRANSFERASE Compound PROTEIN (THYMIDYLATE SYNTHASE) Source Pneumocystis carinii (TYSY_PNECA) Sequence B:  NAEEQQYLNLVQYIINHGEDRPDRTGTGTLSVFAPSPLKF SLRNKTFPLLTTKRVFIRGVIEELLWFIRGETDSLKLREK NIHIWDANGSREYLDSIGLTKRQEGDLGPIYGFQWRHFGA EYIDCKTNYIGQGVDQLANIIQKIRTSPYDRRLILSAWNP ADLEKMALPPCHMFCQFYVHIPSRPELSCQLYQRSCDMGL GVPFNIASYALLTCMIAHVCDLDPGDFIHVMGDCHIYKDH IEALQQQLTRSPRPFPTLSLNRSITDIEDFTLDDFNIQNY HPYETIKMKMSI Description Functional site 1) chain B residue 26 type sequence R description BINDING SITE FOR RESIDUE UMP B 765 source : AC1 2) chain B residue 170 type sequence L description BINDING SITE FOR RESIDUE UMP B 765 source : AC1 3) chain B residue 173 type sequence C description BINDING SITE FOR RESIDUE UMP B 765 source : AC1 4) chain B residue 199 type sequence R description BINDING SITE FOR RESIDUE UMP B 765 source : AC1 5) chain B residue 200 type sequence S description BINDING SITE FOR RESIDUE UMP B 765 source : AC1 6) chain B residue 201 type sequence C description BINDING SITE FOR RESIDUE UMP B 765 source : AC1 7) chain B residue 202 type sequence D description BINDING SITE FOR RESIDUE UMP B 765 source : AC1 8) chain B residue 210 type sequence N description BINDING SITE FOR RESIDUE UMP B 765 source : AC1 9) chain B residue 240 type sequence H description BINDING SITE FOR RESIDUE UMP B 765 source : AC1 10) chain B residue 242 type sequence Y description BINDING SITE FOR RESIDUE UMP B 765 source : AC1 11) chain B residue 153 type sequence R description BINDING SITE FOR RESIDUE UMP A 767 source : AC2 12) chain B residue 154 type sequence R description BINDING SITE FOR RESIDUE UMP A 767 source : AC2 13) chain B residue 173 type ACT_SITE sequence C description Nucleophile => ECO:0000250|UniProtKB:P0A884 source Swiss-Prot : SWS_FT_FI1 14) chain B residue 26 type BINDING sequence R description in other chain => ECO:0000250|UniProtKB:P0A884 source Swiss-Prot : SWS_FT_FI2 15) chain B residue 199 type BINDING sequence R description in other chain => ECO:0000250|UniProtKB:P0A884 source Swiss-Prot : SWS_FT_FI2 16) chain B residue 210 type BINDING sequence N description in other chain => ECO:0000250|UniProtKB:P0A884 source Swiss-Prot : SWS_FT_FI2 17) chain B residue 240 type BINDING sequence H description in other chain => ECO:0000250|UniProtKB:P0A884 source Swiss-Prot : SWS_FT_FI2 18) chain B residue 153 type BINDING sequence R description BINDING => ECO:0000250|UniProtKB:P0A884 source Swiss-Prot : SWS_FT_FI3 19) chain B residue 202 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:P0A884 source Swiss-Prot : SWS_FT_FI3

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