eF-site ID 1cgs-HL PDB Code 1cgs Chain H, L click to enlarge Title LOCAL AND TRANSMITTED CONFORMATIONAL CHANGES ON COMPLEXATION OF AN ANTI-SWEETENER FAB Classification IMMUNOGLOBULIN Compound IGG2B-KAPPA NC6.8 FAB (LIGHT CHAIN) Source (AAB16764) Sequence H:  RVQLLESGAELMKPGASVQISCKATGYTFSEYWIEWVKER PGHGLEWIGEILPGSGRTNYREKFKGKATFTADTSSNTAY MQLSSLTSEDSAVYYCTRGYSSMDYWGQGTSVTVSAAKTT PPSVYPLAPGCGDTTGSSVTLGCLVKGYFPESVTVTWNSG SLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSQTVTCSV AHPASSTTVDKKLE L:  ELVMTQSPLSLPVSLGDQASISCRPSQSLVHSNGNTYLHW YLQKPGQSPKLLIYRVSNRFSGVPDRFSGSGSGTAFTLKI SRVEAEDLGVYFCSQGTHVPYTFGGGTKLELKRADAAPTV SIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSER QNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCE ATHKTSTSPIVKSFNRNEC Description (1)  IGG2B (KAPPA) FAB FRAGMENT AGAINST ANTIGEN N-(P-CYANOPHENYL)-N'-(DIPHENYLEMETHYL) GUANIDINEACETIC ACID Functional site 1) chain L residue 31 type sequence H description HAPTEN BINDING SITE source : LHS 2) chain L residue 37 type sequence Y description HAPTEN BINDING SITE source : LHS 3) chain L residue 39 type sequence H description HAPTEN BINDING SITE source : LHS 4) chain L residue 96 type sequence G description HAPTEN BINDING SITE source : LHS 5) chain L residue 101 type sequence Y description HAPTEN BINDING SITE source : LHS 6) chain H residue 33 type sequence W description HAPTEN BINDING SITE source : LHS 7) chain H residue 35 type sequence E description HAPTEN BINDING SITE source : LHS 8) chain H residue 50 type sequence E description HAPTEN BINDING SITE source : LHS 9) chain H residue 57 type sequence R description HAPTEN BINDING SITE source : LHS 10) chain H residue 59 type sequence N description HAPTEN BINDING SITE source : LHS 11) chain H residue 100 type sequence Y description HAPTEN BINDING SITE source : LHS 12) chain H residue 101 type sequence S description HAPTEN BINDING SITE source : LHS 13) chain H residue 102 type sequence S description HAPTEN BINDING SITE source : LHS 14) chain L residue 197-203 type prosite sequence YTCEATH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH source prosite : PS00290

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