eF-site ID 1cgh-A PDB Code 1cgh Chain A click to enlarge Title Human cathepsin G Classification HYDROLASE/HYDROLASE INHIBITOR Compound CATHEPSIN G Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence A:  IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQY NQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGT LCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYD PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKS SGVPPEVFTRVSSFLPWIRTTMRS Description Functional site 1) chain A residue 57 type sequence H description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 2) chain A residue 177 type sequence P description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 3) chain A residue 178 type sequence R description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 4) chain A residue 190 type sequence A description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 5) chain A residue 191 type sequence F description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 6) chain A residue 192 type sequence K description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 7) chain A residue 193 type sequence G description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 8) chain A residue 194 type sequence D description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 9) chain A residue 195 type sequence S description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 10) chain A residue 214 type sequence S description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 11) chain A residue 215 type sequence Y description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 12) chain A residue 216 type sequence G description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 13) chain A residue 217 type sequence K description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 14) chain A residue 226 type sequence E description BINDING SITE FOR RESIDUE 1ZG A 1 source : AC1 15) chain A residue 65 type CARBOHYD sequence N description N-linked (GlcNAc...) (paucimannose) asparagine; alternate => ECO:0000269|PubMed:26274980 source Swiss-Prot : SWS_FT_FI2 16) chain A residue 57 type ACT_SITE sequence H description Charge relay system => ECO:0000255|PROSITE-ProRule:PRU00274 source Swiss-Prot : SWS_FT_FI1 17) chain A residue 102 type ACT_SITE sequence D description Charge relay system => ECO:0000255|PROSITE-ProRule:PRU00274 source Swiss-Prot : SWS_FT_FI1 18) chain A residue 195 type ACT_SITE sequence S description Charge relay system => ECO:0000255|PROSITE-ProRule:PRU00274 source Swiss-Prot : SWS_FT_FI1 19) chain A residue 53-58 type prosite sequence LTAAHC description TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC source prosite : PS00134 20) chain A residue 189-200 type prosite sequence AAFKGDSGGPLL description TRYPSIN_SER Serine proteases, trypsin family, serine active site. AAfkGDSGGPLL source prosite : PS00135

Display surface Download Links