eF-site ID 1cfh_13-A PDB Code 1cfh Model 13 Chain A click to enlarge Title STRUCTURE OF THE METAL-FREE GAMMA-CARBOXYGLUTAMIC ACID-RICH MEMBRANE BINDING REGION OF FACTOR IX BY TWO-DIMENSIONAL NMR SPECTROSCOPY Classification COAGULATION FACTOR Compound COAGULATION FACTOR IX Source null (FA9_HUMAN) Sequence A:  YNSGKLEEFVQGNLERECMEEKCSFEEAREVFENTERTTE FWKQYVD Description Functional site 1) chain A residue 7 type sequence E description BINDING SITE FOR RESIDUE FMT A 48 source : AC1 2) chain A residue 8 type sequence E description BINDING SITE FOR RESIDUE FMT A 48 source : AC1 3) chain A residue 1 type sequence Y description BINDING SITE FOR RESIDUE FMT A 49 source : AC2 4) chain A residue 8 type sequence E description BINDING SITE FOR RESIDUE FMT A 49 source : AC2 5) chain A residue 15 type sequence E description BINDING SITE FOR RESIDUE FMT A 50 source : AC3 6) chain A residue 17 type sequence E description BINDING SITE FOR RESIDUE FMT A 51 source : AC4 7) chain A residue 22 type sequence K description BINDING SITE FOR RESIDUE FMT A 51 source : AC4 8) chain A residue 20 type sequence E description BINDING SITE FOR RESIDUE FMT A 52 source : AC5 9) chain A residue 21 type sequence E description BINDING SITE FOR RESIDUE FMT A 53 source : AC6 10) chain A residue 24 type sequence S description BINDING SITE FOR RESIDUE FMT A 53 source : AC6 11) chain A residue 26 type sequence E description BINDING SITE FOR RESIDUE FMT A 54 source : AC7 12) chain A residue 27 type sequence E description BINDING SITE FOR RESIDUE FMT A 55 source : AC8 13) chain A residue 30 type sequence E description BINDING SITE FOR RESIDUE FMT A 56 source : AC9 14) chain A residue 31 type sequence V description BINDING SITE FOR RESIDUE FMT A 56 source : AC9 15) chain A residue 32 type sequence F description BINDING SITE FOR RESIDUE FMT A 56 source : AC9 16) chain A residue 32 type sequence F description BINDING SITE FOR RESIDUE FMT A 57 source : BC1 17) chain A residue 33 type sequence E description BINDING SITE FOR RESIDUE FMT A 57 source : BC1 18) chain A residue 36 type sequence E description BINDING SITE FOR RESIDUE FMT A 58 source : BC2 19) chain A residue 40 type sequence E description BINDING SITE FOR RESIDUE FMT A 59 source : BC3 20) chain A residue 17-42 type prosite sequence ECMEEKCSFEEAREVFENTERTTEFW description GLA_1 Vitamin K-dependent carboxylation domain. EcmEEkCsfeearEvfentertte.FW source prosite : PS00011 21) chain A residue 2 type BINDING sequence N description BINDING => ECO:0000269|PubMed:14722079, ECO:0007744|PDB:1NL0 source Swiss-Prot : SWS_FT_FI1 22) chain A residue 1 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:14722079, ECO:0007744|PDB:1NL0 source Swiss-Prot : SWS_FT_FI1 23) chain A residue 8 type BINDING sequence E description via 4-carboxyglutamate => ECO:0000305|PubMed:14722079, ECO:0007744|PDB:1NL0 source Swiss-Prot : SWS_FT_FI2 24) chain A residue 17 type BINDING sequence E description via 4-carboxyglutamate => ECO:0000305|PubMed:14722079, ECO:0007744|PDB:1NL0 source Swiss-Prot : SWS_FT_FI2 25) chain A residue 21 type BINDING sequence E description via 4-carboxyglutamate => ECO:0000305|PubMed:14722079, ECO:0007744|PDB:1NL0 source Swiss-Prot : SWS_FT_FI2 26) chain A residue 27 type BINDING sequence E description via 4-carboxyglutamate => ECO:0000305|PubMed:14722079, ECO:0007744|PDB:1NL0 source Swiss-Prot : SWS_FT_FI2 27) chain A residue 7 type BINDING sequence E description via 4-carboxyglutamate => ECO:0000305|PubMed:14722079, ECO:0007744|PDB:1NL0 source Swiss-Prot : SWS_FT_FI2 28) chain A residue 15 type BINDING sequence E description via 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741 source Swiss-Prot : SWS_FT_FI3 29) chain A residue 20 type BINDING sequence E description via 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741 source Swiss-Prot : SWS_FT_FI3 30) chain A residue 26 type BINDING sequence E description via 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741 source Swiss-Prot : SWS_FT_FI3 31) chain A residue 30 type BINDING sequence E description via 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741 source Swiss-Prot : SWS_FT_FI3 32) chain A residue 36 type BINDING sequence E description via 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741 source Swiss-Prot : SWS_FT_FI3 33) chain A residue 40 type BINDING sequence E description via 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741 source Swiss-Prot : SWS_FT_FI3 34) chain A residue 47 type BINDING sequence D description BINDING => ECO:0000269|PubMed:7606779, ECO:0007744|PDB:1EDM source Swiss-Prot : SWS_FT_FI4 35) chain A residue 33 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 36) chain A residue 36 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 37) chain A residue 40 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 38) chain A residue 15 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 39) chain A residue 17 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 40) chain A residue 20 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 41) chain A residue 21 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 42) chain A residue 26 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 43) chain A residue 27 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 44) chain A residue 30 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 45) chain A residue 7 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 46) chain A residue 8 type MOD_RES sequence E description 4-carboxyglutamate => ECO:0000250|UniProtKB:P00741, ECO:0000255|PROSITE-ProRule:PRU00463 source Swiss-Prot : SWS_FT_FI5 47) chain A residue 39 type CARBOHYD sequence T description O-linked (GalNAc...) threonine => ECO:0000269|PubMed:25456591 source Swiss-Prot : SWS_FT_FI6

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