|
|
eF-site ID
|
1ce1-HLP |
|
PDB Code
|
1ce1 |
|
Chain
|
H, L, P |
|
click to enlarge
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Title
|
1.9A STRUCTURE OF THE THERAPEUTIC ANTIBODY CAMPATH-1H FAB IN COMPLEX WITH A SYNTHETIC PEPTIDE ANTIGEN |
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Classification
|
IMMUNE SYSTEM |
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Compound
|
PROTEIN (CAMPATH-1H:LIGHT CHAIN) |
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Source
|
(1CE1) |
|
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Sequence
|
H: |
QVQLQESGPGLVRPSQTLSLTCTVSGFTFTDFYMNWVRQP
PGRGLEWIGFIRDKAKGYTTEYNPSVKGRVTMLVDTSKNQ
FSLRLSSVTAADTAVYYCAREGHTAAPFDYWGQGSLVTVS
SASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTV
SWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQ
TYICNVNHKPSNTKVDKKVE
|
| L: |
DIQMTQSPSSLSASVGDRVTITCKASQNIDKYLNWYQQKP
GKAPKLLIYNTNNLQTGVPSRFSGSGSGTDFTFTISSLQP
EDIATYYCLQHISRPRTFGQGTKVEIKRTVAAPSVFIFPP
SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG
LSSPVTKSFNR
|
| P: |
GTSSPSAD
|
|
|
Description
|
|
Functional site
|
|
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1)
|
chain |
H |
| residue |
202-208 |
| type |
prosite |
| sequence |
YICNVNH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
|
|
|
2)
|
chain |
L |
| residue |
192-198 |
| type |
prosite |
| sequence |
YACEVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
|
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