|
|
eF-site ID
|
1cd9-ABCD |
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PDB Code
|
1cd9 |
|
Chain
|
A, B, C, D |
|
click to enlarge
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Title
|
2:2 COMPLEX OF G-CSF WITH ITS RECEPTOR |
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Classification
|
CYTOKINE |
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Compound
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PROTEIN (GRANULOCYTE COLONY-STIMULATING FACTOR) |
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Source
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(CSF3R_MOUSE) |
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Sequence
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A: |
GPASSLPQSFLLKCLEQVRKIQGDGAALQEKLCATYKLCH
PEELVLLGHSLGIPWAPLSSCPSQALQLAGCLSQLHSGLF
LYQGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEE
LGMAPALQPTQGAMPAFASAFQRRAGGVLVASHLQSFLEV
SYRVLRHLAQP
|
| B: |
AGYPPASPSNLSCLMHLTTNSLVCQWEPGPETHLPTSFIL
KSFRSRADCQYQGDTIPDCVAKKRQNNCSIPRKNLLLYQY
MAIWVQAENMLGSSESPKLCLDPMDVVKLEPPMLQALDIQ
PGCLWLSWKPWKPSEYMEQECELRYQPQLKGANWTLVFHL
PSSKDQFELCGLHQAPVYTLQMRCIRSSLPGFWSPWSPGL
QLRPTM
|
| C: |
ASSLPQSFLLKCLEQVRKIQGDGAALQEKLCATYKLCHPE
ELVLLGHSLGIPWAPLSSCPSQALQLAGCLSQLHSGLFLY
QGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELG
MAPALQPTQGAMPAFASAFQRRAGGVLVASHLQSFLEVSY
RVLRHLAQP
|
| D: |
GYPPASPSNLSCLMHLTTNSLVCQWEPGPETHLPTSFILK
SFRSRADCQYQGDTIPDCVAKKRQNNCSIPRKNLLLYQYM
AIWVQAENMLGSSESPKLCLDPMDVVKLEPPMLQALDQPG
CLWLSWKPWKPSEYMEQECELRYQPQLKGANWTLVFHLPS
SKDQFELCGLHQAPVYTLQMRCIRSSLPGFWSPWSPGLQL
RPTM
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
67 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
B |
| residue |
160 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
D |
| residue |
67 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
D |
| residue |
160 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
65-90 |
| type |
prosite |
| sequence |
CPSQALQLAGCLSQLHSGLFLYQGLL
|
| description |
INTERLEUKIN_6 Interleukin-6 / G-CSF / MGF signature. CpsqalqlagClsqlhsGLflYqglL
|
| source |
prosite : PS00254
|
|
|
6)
|
chain |
B |
| residue |
10 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10537111
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
D |
| residue |
10 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10537111
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|