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eF-site ID
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1c8m-2 |
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PDB Code
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1c8m |
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Chain
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2 |
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click to enlarge
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Title
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REFINED CRYSTAL STRUCTURE OF HUMAN RHINOVIRUS 16 COMPLEXED WITH VP63843 (PLECONARIL), AN ANTI-PICORNAVIRAL DRUG CURRENTLY IN CLINICAL TRIALS |
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Classification
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VIRUS |
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Compound
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HUMAN RHINOVIRUS 16 COAT PROTEIN |
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Source
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ORGANISM_SCIENTIFIC: Human rhinovirus 16; |
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Sequence
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2: |
SDRIIQITRGDSTITSQDVANAVVGYGVWPHYLTPQDATA
IDKPTQPDTSSNRFYTLDSKMWNSTSKGWWWKLPDALKDM
GIFGENMFYHFLGRSGYTVHVQCNASKFHQGTLLVVMIPE
HQLATVNKGNVNAGYKYTHPGEAGREVGTQVENEKQPSDD
NWLNFDGTLLGNLLIFPHQFINLRSNNSATLIVPYVNAVP
MDSMVRHNNWSLVIIPVCQLQSNNISNIVPITVSISPMCA
EFSGARAKTVVQ
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Description
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Functional site
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1)
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chain |
2 |
| residue |
38 |
| type |
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| sequence |
W
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| description |
RNA OBSERVED INTERACTING WITH THESE RESIDUES ON THE INTERIOR SURFACE OF VIRAL PROTEIN CAPSID. NON-CONSERVATIVE MUTATION OF TRP 2 38 GIVES NON-VIABLE VIRUS.
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| source |
: RNA
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