eF-site ID 1c5f-E PDB Code 1c5f Chain E click to enlarge Title CRYSTAL STRUCTURE OF THE CYCLOPHILIN-LIKE DOMAIN FROM BRUGIA MALAYI COMPLEXED WITH CYCLOSPORIN A Classification ISOMERASE/IMMUNOSUPPRESSANT Compound PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 1 Source Brugia malayi (Filarial nematode worm) (NOR00033) Sequence E:  KDRRRVFLDVTIDGNLAGRIVMELYNDIAPRTCNNFLMLC TGMAGTGKISGKPLHYKGSTFHRVIKNFMIQGGDFTKGDG TGGESIYGGMFDDEEFVMKHDEPFVVSMANKGPNTNGSQF FITTTPAPHLNNIHVVFGKVVSGQEVVTKIEYLKTNSKNR PLADVVILNCGELV Description Functional site 1) chain E residue 66 type sequence R description BINDING SITE FOR CHAIN F OF CYCLOSPORIN A source : AC3 2) chain E residue 71 type sequence F description BINDING SITE FOR CHAIN F OF CYCLOSPORIN A source : AC3 3) chain E residue 74 type sequence Q description BINDING SITE FOR CHAIN F OF CYCLOSPORIN A source : AC3 4) chain E residue 83 type sequence G description BINDING SITE FOR CHAIN F OF CYCLOSPORIN A source : AC3 5) chain E residue 112 type sequence A description BINDING SITE FOR CHAIN F OF CYCLOSPORIN A source : AC3 6) chain E residue 113 type sequence N description BINDING SITE FOR CHAIN F OF CYCLOSPORIN A source : AC3 7) chain E residue 114 type sequence K description BINDING SITE FOR CHAIN F OF CYCLOSPORIN A source : AC3 8) chain E residue 122 type sequence Q description BINDING SITE FOR CHAIN F OF CYCLOSPORIN A source : AC3 9) chain E residue 124 type sequence F description BINDING SITE FOR CHAIN F OF CYCLOSPORIN A source : AC3 10) chain E residue 132 type sequence H description BINDING SITE FOR CHAIN F OF CYCLOSPORIN A source : AC3 11) chain E residue 137 type sequence H description BINDING SITE FOR CHAIN F OF CYCLOSPORIN A source : AC3 12) chain E residue 46 type sequence M description BINDING SITE FOR CHAIN H OF CYCLOSPORIN A source : AC4 13) chain E residue 47 type sequence A description BINDING SITE FOR CHAIN H OF CYCLOSPORIN A source : AC4 14) chain E residue 89 type sequence I description BINDING SITE FOR CHAIN H OF CYCLOSPORIN A source : AC4 15) chain E residue 34 type sequence R description BINDING SITE FOR CHAIN P OF CYCLOSPORIN A source : AC8 16) chain E residue 90 type sequence Y description BINDING SITE FOR CHAIN P OF CYCLOSPORIN A source : AC8

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