eF-site ID 1c5f-AKM PDB Code 1c5f Chain A, K, M click to enlarge Title CRYSTAL STRUCTURE OF THE CYCLOPHILIN-LIKE DOMAIN FROM BRUGIA MALAYI COMPLEXED WITH CYCLOSPORIN A Classification ISOMERASE/IMMUNOSUPPRESSANT Compound PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 1 Source Brugia malayi (Filarial nematode worm) (NOR00033) Sequence A:  MSKKDRRRVFLDVTIDGNLAGRIVMELYNDIAPRTCNNFL MLCTGMAGTGKISGKPLHYKGSTFHRVIKNFMIQGGDFTK GDGTGGESIYGGMFDDEEFVMKHDEPFVVSMANKGPNTNG SQFFITTTPAPHLNNIHVVFGKVVSGQEVVTKIEYLKTNS KNRPLADVVILNCGELV K:  KKDRRRVFLDVTIDGNLAGRIVMELYNDIAPRTCNNFLML CTGMAGTGKISGKPLHYKGSTFHRVIKNFMIQGGDFTKGD GTGGESIYGGMFDDEEFVMKHDEPFVVSMANKGPNTNGSQ FFITTTPAPHLNNIHVVFGKVVSGQEVVTKIEYLKTNSKN RPLADVVILNCGELV M:  KKDRRRVFLDVTIDGNLAGRIVMELYNDIAPRTCNNFLML CTGMAGTGKISGKPLHYKGSTFHRVIKNFMIQGGDFTKGD GTGGESIYGGMFDDEEFVMKHDEPFVVSMANKGPNTNGSQ FFITTTPAPHLNNIHVVFGKVVSGQEVVTKIEYLKTNSKN RPLADVVILNCGELV Description Functional site 1) chain A residue 66 type sequence R description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 2) chain A residue 71 type sequence F description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 3) chain A residue 74 type sequence Q description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 4) chain A residue 83 type sequence G description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 5) chain A residue 112 type sequence A description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 6) chain A residue 113 type sequence N description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 7) chain A residue 114 type sequence K description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 8) chain A residue 122 type sequence Q description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 9) chain A residue 124 type sequence F description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 10) chain A residue 132 type sequence H description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 11) chain A residue 137 type sequence H description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 12) chain K residue 66 type sequence R description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 13) chain K residue 71 type sequence F description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 14) chain K residue 74 type sequence Q description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 15) chain K residue 83 type sequence G description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 16) chain K residue 112 type sequence A description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 17) chain K residue 113 type sequence N description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 18) chain K residue 114 type sequence K description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 19) chain K residue 122 type sequence Q description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 20) chain K residue 124 type sequence F description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 21) chain K residue 132 type sequence H description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 22) chain K residue 137 type sequence H description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 23) chain M residue 132 type sequence H description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 24) chain M residue 136 type sequence I description BINDING SITE FOR CHAIN L OF CYCLOSPORIN A source : AC6 25) chain K residue 132 type sequence H description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 26) chain K residue 136 type sequence I description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 27) chain M residue 66 type sequence R description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 28) chain M residue 71 type sequence F description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 29) chain M residue 74 type sequence Q description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 30) chain M residue 83 type sequence G description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 31) chain M residue 112 type sequence A description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 32) chain M residue 113 type sequence N description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 33) chain M residue 114 type sequence K description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 34) chain M residue 122 type sequence Q description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 35) chain M residue 124 type sequence F description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 36) chain M residue 132 type sequence H description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 37) chain M residue 137 type sequence H description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : AC7 38) chain A residue 59-76 type prosite sequence YKGSTFHRVIKNFMIQGG description CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YkgStFHRVIknFMiQGG source prosite : PS00170

Display surface Download Links