eF-site ID 1c5f-A PDB Code 1c5f Chain A click to enlarge Title CRYSTAL STRUCTURE OF THE CYCLOPHILIN-LIKE DOMAIN FROM BRUGIA MALAYI COMPLEXED WITH CYCLOSPORIN A Classification ISOMERASE/IMMUNOSUPPRESSANT Compound PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 1 Source Brugia malayi (Filarial nematode worm) (NOR00033) Sequence A:  MSKKDRRRVFLDVTIDGNLAGRIVMELYNDIAPRTCNNFL MLCTGMAGTGKISGKPLHYKGSTFHRVIKNFMIQGGDFTK GDGTGGESIYGGMFDDEEFVMKHDEPFVVSMANKGPNTNG SQFFITTTPAPHLNNIHVVFGKVVSGQEVVTKIEYLKTNS KNRPLADVVILNCGELV Description Functional site 1) chain A residue 66 type sequence R description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 2) chain A residue 71 type sequence F description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 3) chain A residue 74 type sequence Q description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 4) chain A residue 83 type sequence G description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 5) chain A residue 112 type sequence A description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 6) chain A residue 113 type sequence N description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 7) chain A residue 114 type sequence K description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 8) chain A residue 122 type sequence Q description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 9) chain A residue 124 type sequence F description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 10) chain A residue 132 type sequence H description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 11) chain A residue 137 type sequence H description BINDING SITE FOR CHAIN B OF CYCLOSPORIN A source : AC1 12) chain A residue 59-76 type prosite sequence YKGSTFHRVIKNFMIQGG description CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YkgStFHRVIknFMiQGG source prosite : PS00170

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