|
|
eF-site ID
|
1c4z-D |
|
PDB Code
|
1c4z |
|
Chain
|
D |
|
click to enlarge
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Title
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STRUCTURE OF AN E6AP-UBCH7 COMPLEX: INSIGHTS INTO THE UBIQUITINATION PATHWAY |
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Classification
|
LIGASE |
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Compound
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UBIQUITIN-PROTEIN LIGASE E3A |
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Source
|
(UB2L3_HUMAN) |
|
|
Sequence
|
D: |
SRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDN
PPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKG
QVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRA
DLAEEYSKDRKKFCKNAEEFTKKY
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Description
|
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Functional site
|
|
|
1)
|
chain |
D |
| residue |
86 |
| type |
catalytic |
| sequence |
C
|
| description |
438
|
| source |
MCSA : MCSA1
|
|
|
2)
|
chain |
D |
| residue |
75-90 |
| type |
prosite |
| sequence |
YHPNIDEKGQVCLPVI
|
| description |
UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNIdek.GqVCLpvI
|
| source |
prosite : PS00183
|
|
|
3)
|
chain |
D |
| residue |
86 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000255|PROSITE-ProRule:PRU10133
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
D |
| residue |
131 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI2
|
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