|
|
eF-site ID
|
1c4z-C |
|
PDB Code
|
1c4z |
|
Chain
|
C |
|
click to enlarge
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Title
|
STRUCTURE OF AN E6AP-UBCH7 COMPLEX: INSIGHTS INTO THE UBIQUITINATION PATHWAY |
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Classification
|
LIGASE |
|
Compound
|
UBIQUITIN-PROTEIN LIGASE E3A |
|
Source
|
(UB2L3_HUMAN) |
|
|
Sequence
|
C: |
NPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEF
EGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDESTKLF
WFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYR
KLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMIT
FQISQTDLFGNPMMYDLKENGDKIPITNENRKEFVNLYSD
YILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLI
CGSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTD
EQKRLFLQFTTGTDRAPVGGLGKLKMIIAKNGPDTERLPT
SHTCFNVLLLPEYSSKEKLKERLLKAITYA
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Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
506 |
| type |
catalytic |
| sequence |
R
|
| description |
438
|
| source |
MCSA : MCSA3
|
|
|
2)
|
chain |
C |
| residue |
539 |
| type |
catalytic |
| sequence |
E
|
| description |
438
|
| source |
MCSA : MCSA3
|
|
|
3)
|
chain |
C |
| residue |
550 |
| type |
catalytic |
| sequence |
E
|
| description |
438
|
| source |
MCSA : MCSA3
|
|
|
4)
|
chain |
C |
| residue |
607 |
| type |
catalytic |
| sequence |
D
|
| description |
438
|
| source |
MCSA : MCSA3
|
|
|
5)
|
chain |
C |
| residue |
818 |
| type |
catalytic |
| sequence |
H
|
| description |
438
|
| source |
MCSA : MCSA3
|
|
|
6)
|
chain |
C |
| residue |
820 |
| type |
catalytic |
| sequence |
C
|
| description |
438
|
| source |
MCSA : MCSA3
|
|
|
7)
|
chain |
C |
| residue |
820 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000255|PROSITE-ProRule:PRU10133
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
C |
| residue |
636 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|