eF-site ID 1c3e-B PDB Code 1c3e Chain B click to enlarge Title NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLATE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID. Classification TRANSFERASE Compound GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE Source Escherichia coli (strain K12) (1C3E) Sequence B:  MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADA FGLERARQAGIATHTLIASAFDSREAYDRELIHEIDMYAP DVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGD SEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLDG QRLPPQGYA Description Functional site 1) chain B residue 64 type sequence R description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 2) chain B residue 88 type sequence F description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 3) chain B residue 89 type sequence M description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 4) chain B residue 90 type sequence R description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 5) chain B residue 91 type sequence I description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 6) chain B residue 92 type sequence L description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 7) chain B residue 97 type sequence V description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 8) chain B residue 106 type sequence N description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 9) chain B residue 108 type sequence H description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 10) chain B residue 118 type sequence L description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 11) chain B residue 139 type sequence V description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 12) chain B residue 140 type sequence T description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 13) chain B residue 142 type sequence E description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 14) chain B residue 144 type sequence D description BINDING SITE FOR RESIDUE NHR B 222 source : AC3 15) chain B residue 10 type sequence N description BINDING SITE FOR RESIDUE GAR B 223 source : AC4 16) chain B residue 11 type sequence G description BINDING SITE FOR RESIDUE GAR B 223 source : AC4 17) chain B residue 12 type sequence S description BINDING SITE FOR RESIDUE GAR B 223 source : AC4 18) chain B residue 13 type sequence N description BINDING SITE FOR RESIDUE GAR B 223 source : AC4 19) chain B residue 87 type sequence G description BINDING SITE FOR RESIDUE GAR B 223 source : AC4 20) chain B residue 88 type sequence F description BINDING SITE FOR RESIDUE GAR B 223 source : AC4 21) chain B residue 89 type sequence M description BINDING SITE FOR RESIDUE GAR B 223 source : AC4 22) chain B residue 107 type sequence I description BINDING SITE FOR RESIDUE GAR B 223 source : AC4 23) chain B residue 109 type sequence P description BINDING SITE FOR RESIDUE GAR B 223 source : AC4 24) chain B residue 173 type sequence E description BINDING SITE FOR RESIDUE GAR B 223 source : AC4

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