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eF-site ID
|
1bxl-AB |
|
PDB Code
|
1bxl |
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Chain
|
A, B |
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click to enlarge
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Title
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STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE |
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Classification
|
COMPLEX (APOPTOSIS/PEPTIDE) |
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Compound
|
BCL-XL |
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Source
|
Homo sapiens (Human) (BAK_HUMAN) |
|
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Sequence
|
A: |
MSMAMSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTE
APEGTESEAVKQALREAGDEFELRYRRAFSDLTSQLHITP
GTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVD
KEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG
NNAAAESRKGQERLEHHHHHH
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| B: |
GQVGRQLAIIGDDINR
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
130-148 |
| type |
prosite |
| sequence |
LFRDGVNWGRIVAFFSFGG
|
| description |
BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG
|
| source |
prosite : PS01080
|
|
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2)
|
chain |
A |
| residue |
181-192 |
| type |
prosite |
| sequence |
WIQENGGWDTFV
|
| description |
BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV
|
| source |
prosite : PS01258
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|
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3)
|
chain |
A |
| residue |
86-100 |
| type |
prosite |
| sequence |
VKQALREAGDEFELR
|
| description |
BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR
|
| source |
prosite : PS01259
|
|
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4)
|
chain |
A |
| residue |
4-24 |
| type |
prosite |
| sequence |
SNRELVVDFLSYKLSQKGYSW
|
| description |
BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW
|
| source |
prosite : PS01260
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