eF-site ID 1bq6-A PDB Code 1bq6 Chain A click to enlarge Title CHALCONE SYNTHASE FROM ALFALFA WITH COENZYME A Classification TRANSFERASE Compound CHALCONE SYNTHASE Source Medicago sativa (Alfalfa) (CHS2_MEDSA) Sequence A:  VSVSEIRKAQRAEGPATILAIGTANPANCVEQSTYPDFYF KITNSEHKTELKEKFQRMCDKSMIKRRYMYLTEEILKENP NVCEYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPK SKITHLIVCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQ QGXFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGP SDTHLDSLVGQALFGDGAAALIVGSDPVPEIEKPIFEMVW TAQTIAPDSEGAIDGHLREAGLTFHLLKDVPGIVSKNITK ALVEAFEPLGISDYNSIFWIAHPGGPAILDQVEQKLALKP EKMNATREVLSEYGNMSSACVLFILDEMRKKSTQNGLKTT GEGLEWGVLFGFGPGLTIETVVLRSVAI Description Functional site 1) chain A residue 164 type sequence X description CATALYTIC SITE source : CYS 2) chain A residue 2 type sequence V description BINDING SITE FOR RESIDUE SO4 A 391 source : AC1 3) chain A residue 3 type sequence S description BINDING SITE FOR RESIDUE SO4 A 391 source : AC1 4) chain A residue 4 type sequence V description BINDING SITE FOR RESIDUE SO4 A 391 source : AC1 5) chain A residue 5 type sequence S description BINDING SITE FOR RESIDUE SO4 A 391 source : AC1 6) chain A residue 385 type sequence R description BINDING SITE FOR RESIDUE SO4 A 391 source : AC1 7) chain A residue 55 type sequence K description BINDING SITE FOR RESIDUE COA A 390 source : AC2 8) chain A residue 58 type sequence R description BINDING SITE FOR RESIDUE COA A 390 source : AC2 9) chain A residue 59 type sequence M description BINDING SITE FOR RESIDUE COA A 390 source : AC2 10) chain A residue 62 type sequence K description BINDING SITE FOR RESIDUE COA A 390 source : AC2 11) chain A residue 164 type sequence X description BINDING SITE FOR RESIDUE COA A 390 source : AC2 12) chain A residue 210 type sequence V description BINDING SITE FOR RESIDUE COA A 390 source : AC2 13) chain A residue 214 type sequence L description BINDING SITE FOR RESIDUE COA A 390 source : AC2 14) chain A residue 265 type sequence F description BINDING SITE FOR RESIDUE COA A 390 source : AC2 15) chain A residue 267 type sequence L description BINDING SITE FOR RESIDUE COA A 390 source : AC2 16) chain A residue 271 type sequence V description BINDING SITE FOR RESIDUE COA A 390 source : AC2 17) chain A residue 305 type sequence G description BINDING SITE FOR RESIDUE COA A 390 source : AC2 18) chain A residue 306 type sequence G description BINDING SITE FOR RESIDUE COA A 390 source : AC2 19) chain A residue 307 type sequence P description BINDING SITE FOR RESIDUE COA A 390 source : AC2 20) chain A residue 308 type sequence A description BINDING SITE FOR RESIDUE COA A 390 source : AC2 21) chain A residue 336 type sequence N description BINDING SITE FOR RESIDUE COA A 390 source : AC2 22) chain A residue 164 type ACT_SITE sequence X description Acyl-thioester intermediate => ECO:0000305 source Swiss-Prot : SWS_FT_FI1 23) chain A residue 164 type catalytic sequence X description 355 source MCSA : MCSA1 24) chain A residue 215 type catalytic sequence F description 355 source MCSA : MCSA1 25) chain A residue 303 type catalytic sequence H description 355 source MCSA : MCSA1 26) chain A residue 336 type catalytic sequence N description 355 source MCSA : MCSA1 27) chain A residue 55 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 28) chain A residue 216 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI2 29) chain A residue 156-172 type prosite sequence RYMMYQQGXFAGGTVLR description CHALCONE_SYNTH Chalcone and stilbene synthases active site. RYmMyQqGCFAGGTvLR source prosite : PS00441 30) chain A residue 308 type BINDING sequence A description BINDING => ECO:0000269|PubMed:10426957, ECO:0000269|PubMed:10653632 source Swiss-Prot : SWS_FT_FI4 31) chain A residue 197 type BINDING sequence T description BINDING => ECO:0000269|PubMed:10426957 source Swiss-Prot : SWS_FT_FI3

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