eF-site ID 1boy-A PDB Code 1boy Chain A click to enlarge Title EXTRACELLULAR REGION OF HUMAN TISSUE FACTOR Classification CLASS 2 CYTOKINE RECEPTOR Compound HUMAN TISSUE FACTOR Source null (TF_HUMAN) Sequence A:  TTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKS GDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGN VESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTK VNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSS SGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKS TDSPVECMGQE Description (1)  HUMAN TISSUE FACTOR Functional site 1) chain A residue 135 type sequence R description CORE BINDING SITE FOR FACTOR VIIA FORMING CONCAVITY BETWEEN 'FINGER' AND DOMAIN 1. source : 7A1 2) chain A residue 140 type sequence F description CORE BINDING SITE FOR FACTOR VIIA FORMING CONCAVITY BETWEEN 'FINGER' AND DOMAIN 1. source : 7A1 3) chain A residue 133 type sequence L description CORE BINDING SITE FOR FACTOR VIIA FORMING CONCAVITY BETWEEN 'FINGER' AND DOMAIN 1. source : 7A1 4) chain A residue 20 type sequence K description CORE BINDING SITE FOR FACTOR VIIA FORMING CONCAVITY BETWEEN 'FINGER' AND DOMAIN 1. source : 7A1 5) chain A residue 60 type sequence T description CORE BINDING SITE FOR FACTOR VIIA FORMING CONCAVITY BETWEEN 'FINGER' AND DOMAIN 1. source : 7A1 6) chain A residue 58 type sequence D description CORE BINDING SITE FOR FACTOR VIIA FORMING CONCAVITY BETWEEN 'FINGER' AND DOMAIN 1. source : 7A1 7) chain A residue 22 type sequence I description CORE BINDING SITE FOR FACTOR VIIA FORMING CONCAVITY BETWEEN 'FINGER' AND DOMAIN 1. source : 7A1 8) chain A residue 24 type sequence E description CORE BINDING SITE FOR FACTOR VIIA FORMING CONCAVITY BETWEEN 'FINGER' AND DOMAIN 1. source : 7A1 9) chain A residue 110 type sequence Q description CORE BINDING SITE FOR FACTOR VIIA FORMING CONCAVITY BETWEEN 'FINGER' AND DOMAIN 1. source : 7A1 10) chain A residue 207 type sequence V description CORE BINDING SITE FOR FACTOR VIIA FORMING CONCAVITY BETWEEN 'FINGER' AND DOMAIN 1. source : 7A1 11) chain A residue 48 type sequence K description DISTAL PART OF BINDING SITE FOR FACTOR VIIA ON CONVEX SURFACE DOMAIN 1 (EXTENDS TO TYR 78 IN HYDROPHOBIC PATCH). source : 7A2 12) chain A residue 46 type sequence K description DISTAL PART OF BINDING SITE FOR FACTOR VIIA ON CONVEX SURFACE DOMAIN 1 (EXTENDS TO TYR 78 IN HYDROPHOBIC PATCH). source : 7A2 13) chain A residue 37 type sequence Q description DISTAL PART OF BINDING SITE FOR FACTOR VIIA ON CONVEX SURFACE DOMAIN 1 (EXTENDS TO TYR 78 IN HYDROPHOBIC PATCH). source : 7A2 14) chain A residue 44 type sequence D description DISTAL PART OF BINDING SITE FOR FACTOR VIIA ON CONVEX SURFACE DOMAIN 1 (EXTENDS TO TYR 78 IN HYDROPHOBIC PATCH). source : 7A2 15) chain A residue 45 type sequence W description DISTAL PART OF BINDING SITE FOR FACTOR VIIA ON CONVEX SURFACE DOMAIN 1 (EXTENDS TO TYR 78 IN HYDROPHOBIC PATCH). source : 7A2 16) chain A residue 78 type sequence Y description DISTAL PART OF BINDING SITE FOR FACTOR VIIA ON CONVEX SURFACE DOMAIN 1 (EXTENDS TO TYR 78 IN HYDROPHOBIC PATCH). source : 7A2 17) chain A residue 165 type sequence K description SITE OF INTERACTION WITH MACROMOLECULAR SUBSTRATE XA WHICH MAY EXTEND OVER 20 RESIDUES (154 - 174). source : XA1 18) chain A residue 166 type sequence K description SITE OF INTERACTION WITH MACROMOLECULAR SUBSTRATE XA WHICH MAY EXTEND OVER 20 RESIDUES (154 - 174). source : XA1 19) chain A residue 124 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 20) chain A residue 137 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 21) chain A residue 45-62 type prosite sequence WKSKCFYTTDTECDLTDE description TISSUE_FACTOR Tissue factor signature. WKsKCfyTtDTECDLTDE source prosite : PS00621

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