|
|
eF-site ID
|
1biu-ABC |
|
PDB Code
|
1biu |
|
Chain
|
A, B, C |
|
click to enlarge
|
|
|
Title
|
HIV-1 INTEGRASE CORE DOMAIN COMPLEXED WITH MG++ |
|
Classification
|
DNA INTEGRATION |
|
Compound
|
HIV-1 INTEGRASE |
|
Source
|
Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1) (POL_HV1N5) |
|
|
Sequence
|
A: |
CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQ
ETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACEWGGI
KQEFGQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFI
HNKKRKGGIGGYSAGERIVDIIATDIQ
|
| B: |
CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQ
ETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACEWGGI
KQEFGGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIH
NKKRKGGIGGYSAGERIVDIIATDIQ
|
| C: |
CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQ
ETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACEWGGI
KQEFGGVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIH
NKKRKGGIGGYSAGERIVDIIATDIQ
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
64 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG A 1244
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
65 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE MG A 1244
|
| source |
: AC1
|
|
|
3)
|
chain |
B |
| residue |
64 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG B 1399
|
| source |
: AC2
|
|
|
4)
|
chain |
B |
| residue |
116 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG B 1399
|
| source |
: AC2
|
|
|
5)
|
chain |
C |
| residue |
64 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG C 1437
|
| source |
: AC3
|
|
|
6)
|
chain |
C |
| residue |
116 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MG C 1437
|
| source |
: AC3
|
|
|
7)
|
chain |
A |
| residue |
57 |
| type |
BINDING |
| sequence |
S
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
A |
| residue |
58 |
| type |
BINDING |
| sequence |
P
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
B |
| residue |
57 |
| type |
BINDING |
| sequence |
S
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
B |
| residue |
58 |
| type |
BINDING |
| sequence |
P
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
11)
|
chain |
C |
| residue |
57 |
| type |
BINDING |
| sequence |
S
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
12)
|
chain |
C |
| residue |
58 |
| type |
BINDING |
| sequence |
P
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|