eF-site ID 1bi4-ABC PDB Code 1bi4 Chain A, B, C click to enlarge Title CATALYTIC DOMAIN OF HIV-1 INTEGRASE Classification DNA INTEGRATION Compound INTEGRASE Source Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1) (POL_HV1N5) Sequence A:  SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQE TAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIK QEFGIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHK RKGGIGGYSAGERIVDIIATDI B:  SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQE TAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGIK QEFLIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNHK RKGGIGGYSAGERIVDIIATDIQ C:  MHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVI PAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAA CWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQA EHLKTAVQMAVFIHNHKRKGGIGGYSAGERIVDIIATDIQ Description Functional site 1) chain C residue 64 type sequence D description ACTIVE SITE. MG-BINDING SITE. source : ACT 2) chain C residue 116 type sequence D description ACTIVE SITE. MG-BINDING SITE. source : ACT 3) chain C residue 152 type sequence E description ACTIVE SITE. MG-BINDING SITE. source : ACT 4) chain B residue 65 type BINDING sequence C description source Swiss-Prot : SWS_FT_FI1 5) chain B residue 117 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI1 6) chain C residue 65 type BINDING sequence C description source Swiss-Prot : SWS_FT_FI1 7) chain C residue 117 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI1 8) chain B residue 153 type BINDING sequence S description BINDING => ECO:0000250|UniProtKB:P04585 source Swiss-Prot : SWS_FT_FI2 9) chain C residue 153 type BINDING sequence S description BINDING => ECO:0000250|UniProtKB:P04585 source Swiss-Prot : SWS_FT_FI2

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