|
|
eF-site ID
|
1bbz-A |
|
PDB Code
|
1bbz |
|
Chain
|
A |
|
click to enlarge
|
|
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Title
|
CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH A DESIGNED HIGH-AFFINITY PEPTIDE LIGAND: IMPLICATIONS FOR SH3-LIGAND INTERACTIONS |
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Classification
|
COMPLEX (TRANSFERASE/PEPTIDE) |
|
Compound
|
ABL TYROSINE KINASE |
|
Source
|
Homo sapiens (Human) (1BBZ) |
|
|
Sequence
|
A: |
NLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQ
TKNGQGWVPSNYITPVNS
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
31 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE SO4 A 3000
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
32 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE SO4 A 3000
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
7 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:16912036, ECO:0000269|PubMed:18775435
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
52 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine => ECO:0000269|PubMed:16912036
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|