|
|
eF-site ID
|
1b96-ABCD |
|
PDB Code
|
1b96 |
|
Chain
|
A, B, C, D |
|
click to enlarge
|
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Title
|
ANALYSIS OF A MUTATIONAL HOT-SPOT IN THE ECORV RESTRICTION ENDONUCLEASE: A CATALYTIC ROLE FOR A MAIN CHAIN CARBONYL GROUP |
|
Classification
|
HYDROLASE/DNA |
|
Compound
|
DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3') |
|
Source
|
Escherichia coli (1B96) |
|
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Sequence
|
A: |
SLRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTKVLS
TIFELFSRPIINKIAEKHGYIVEEPKQENHYPDFTLYKPS
EPNKKIAIDIKTTYTNKENEKIKFTLGGYTSFIRNNTKNI
VYPFDQYIAHWIIGYVYTRVATRKSSLKTYNINELNEIPK
PYKGVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVE
GKGIFDSEDEFLDYWRNYERTSQLRNDKYNNISEYRNWIY
RGRK
|
| B: |
SLRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTKVLS
TIFELFSRPIINKIAEKHGYIVEEPKQENHYPDFTLYKPS
EPNKKIAIDIKTTYTNKENEKIKFTLGGYTSFIRNNTKNI
VYPFDQYIAHWIIGYVYTRVATRKSSLKTYNINELNEIPK
PYKGVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVE
GKGIFDSEDEFLDYWRNYERTSQLRNDKYNNISEYRNWIY
RGRK
|
| C: |
AAAGATATCTT
|
| D: |
AAAGATATCTT
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
46 |
| type |
BINDING |
| sequence |
L
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
A |
| residue |
75 |
| type |
BINDING |
| sequence |
F
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
A |
| residue |
91 |
| type |
BINDING |
| sequence |
I
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
B |
| residue |
46 |
| type |
BINDING |
| sequence |
L
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
B |
| residue |
75 |
| type |
BINDING |
| sequence |
F
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
B |
| residue |
91 |
| type |
BINDING |
| sequence |
I
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
A |
| residue |
75 |
| type |
ACT_SITE |
| sequence |
F
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
A |
| residue |
91 |
| type |
ACT_SITE |
| sequence |
I
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
A |
| residue |
93 |
| type |
ACT_SITE |
| sequence |
T
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
B |
| residue |
75 |
| type |
ACT_SITE |
| sequence |
F
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
11)
|
chain |
B |
| residue |
91 |
| type |
ACT_SITE |
| sequence |
I
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
12)
|
chain |
B |
| residue |
93 |
| type |
ACT_SITE |
| sequence |
T
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|