eF-site ID 1b92-A PDB Code 1b92 Chain A click to enlarge Title MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY Classification TRANSFERASE Compound PROTEIN (INTEGRASE) Source Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1) (POL_HV1N5) Sequence A:  CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQ ETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAACWWAGI KQEFGAVIESMNKELKKIIGQVRDQAEHLKTAVQMAVFIH NKKRKGGYSAGERIVDIIATDIQT Description Functional site 1) chain A residue 65 type sequence C description BINDING SITE FOR RESIDUE CAC A 300 source : AC1 2) chain A residue 97 type sequence T description BINDING SITE FOR RESIDUE CAC A 300 source : AC1 3) chain A residue 120 type sequence N description BINDING SITE FOR RESIDUE CAC A 300 source : AC1 4) chain A residue 121 type sequence F description BINDING SITE FOR RESIDUE CAC A 400 source : AC2 5) chain A residue 126 type sequence V description BINDING SITE FOR RESIDUE CAC A 400 source : AC2 6) chain A residue 130 type sequence C description BINDING SITE FOR RESIDUE CAC A 400 source : AC2 7) chain A residue 135 type sequence I description BINDING SITE FOR RESIDUE CAC A 400 source : AC2 8) chain A residue 136 type sequence K description BINDING SITE FOR RESIDUE CAC A 400 source : AC2 9) chain A residue 137 type sequence Q description BINDING SITE FOR RESIDUE CAC A 400 source : AC2 10) chain A residue 71 type sequence K description BINDING SITE FOR RESIDUE SO4 A 1 source : AC3 11) chain A residue 166 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1 source : AC3 12) chain A residue 171 type sequence H description BINDING SITE FOR RESIDUE SO4 A 1 source : AC3 13) chain A residue 172 type sequence L description BINDING SITE FOR RESIDUE SO4 A 1 source : AC3 14) chain A residue 57 type BINDING sequence S description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 15) chain A residue 58 type BINDING sequence P description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1

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