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eF-site ID
|
1b72-ABDE |
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PDB Code
|
1b72 |
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Chain
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A, B, D, E |
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click to enlarge
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Title
|
PBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX |
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Classification
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PROTEIN/DNA |
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Compound
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DNA (5'-D(*AP*CP*TP*CP*TP*AP*TP*GP*AP*TP*TP*GP*AP*TP*CP*GP*GP*CP*TP*G)-3') |
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Source
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null (1B72) |
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Sequence
|
A: |
ARTFDWMKVLRTNFTTRQLTELEKEFHFNKYLSRARRVEI
AATLELNETQVKIWFQNRRMKQKKRERE
|
| B: |
RKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCG
ITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAA
|
| D: |
ACTCTATGATTGATCGGCTG
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| E: |
TCAGCCGATCAATCATAGAG
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
236-259 |
| type |
prosite |
| sequence |
IAATLELNETQVKIWFQNRRMKQK
|
| description |
HOMEOBOX_1 'Homeobox' domain signature. IAatLeLNetQVKIWFqNrrmkqK
|
| source |
prosite : PS00027
|
|
|
2)
|
chain |
B |
| residue |
269-292 |
| type |
prosite |
| sequence |
LAKKCGITVSQVSNWFGNKRIRYK
|
| description |
HOMEOBOX_1 'Homeobox' domain signature. IAatLeLNetQVKIWFqNrrmkqK
|
| source |
prosite : PS00027
|
|
|
3)
|
chain |
B |
| residue |
286 |
| type |
SITE |
| sequence |
N
|
| description |
Required for binding to the NFIL3 promoter => ECO:0000250|UniProtKB:P41778
|
| source |
Swiss-Prot : SWS_FT_FI2
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