eF-site ID 1b6p-B PDB Code 1b6p Chain B click to enlarge Title HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 7 Classification HYDROLASE/HYDROLASE INHIBITOR Compound RETROPEPSIN Source ORGANISM_SCIENTIFIC: Human immunodeficiency virus 1; Sequence B:  PQITLWKRPLVTIRIGGQLKEALLDTGADDTVIEEMNLPG KWKPKMIGGIGGFIKVRQYDQIPVEIXGHKAIGTVLVGPT PVNIIGRNLLTQIGXTLNF Description Functional site 1) chain B residue 101 type sequence P description BINDING SITE FOR RESIDUE SO4 B 501 source : AC1 2) chain B residue 155 type sequence K description BINDING SITE FOR RESIDUE SO4 B 501 source : AC1 3) chain B residue 116 type sequence G description BINDING SITE FOR RESIDUE SO4 A 503 source : AC3 4) chain B residue 117 type sequence G description BINDING SITE FOR RESIDUE SO4 A 503 source : AC3 5) chain B residue 108 type sequence R description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 6) chain B residue 125 type sequence D description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 7) chain B residue 127 type sequence G description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 8) chain B residue 129 type sequence D description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 9) chain B residue 130 type sequence D description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 10) chain B residue 132 type sequence V description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 11) chain B residue 147 type sequence I description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 12) chain B residue 148 type sequence G description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 13) chain B residue 149 type sequence G description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 14) chain B residue 150 type sequence I description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 15) chain B residue 181 type sequence P description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 16) chain B residue 184 type sequence I description BINDING SITE FOR RESIDUE PI7 A 201 source : AC4 17) chain B residue 178 type SITE sequence G description Cleavage; by viral protease => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 18) chain B residue 178 type MOD_RES sequence G description Phosphotyrosine; by host => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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