|
|
eF-site ID
|
1b2d-AB |
|
PDB Code
|
1b2d |
|
Chain
|
A, B |
|
click to enlarge
|
|
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Title
|
PH AFFECTS GLU B13 SWITCHING AND SULFATE BINDING IN CUBIC INSULIN CRYSTALS (PH 6.35 COORDINATES) |
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Classification
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HORMONE/GROWTH FACTOR |
|
Compound
|
PROTEIN (INSULIN A CHAIN) |
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Source
|
ORGANISM_COMMON: pig; ORGANISM_SCIENTIFIC: Sus scrofa; |
|
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Sequence
|
A: |
GIVEQCCTSICSLYQLENYCN
|
| B: |
FVNQHLCGSHLVEALYLVCGERGFFYTPKA
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
14 |
| type |
|
| sequence |
Y
|
| description |
BINDING SITE FOR RESIDUE SO4 B 100
|
| source |
: AC1
|
|
|
2)
|
chain |
B |
| residue |
1 |
| type |
|
| sequence |
F
|
| description |
BINDING SITE FOR RESIDUE SO4 B 100
|
| source |
: AC1
|
|
|
3)
|
chain |
B |
| residue |
1 |
| type |
|
| sequence |
F
|
| description |
BINDING SITE FOR RESIDUE SO4 B 100
|
| source |
: AC1
|
|
|
4)
|
chain |
B |
| residue |
2 |
| type |
|
| sequence |
V
|
| description |
BINDING SITE FOR RESIDUE SO4 B 100
|
| source |
: AC1
|
|
|
5)
|
chain |
B |
| residue |
3 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE SO4 B 100
|
| source |
: AC1
|
|
|
6)
|
chain |
B |
| residue |
4 |
| type |
|
| sequence |
Q
|
| description |
BINDING SITE FOR RESIDUE SO4 B 100
|
| source |
: AC1
|
|
|
7)
|
chain |
A |
| residue |
6-20 |
| type |
prosite |
| sequence |
CCTSICSLYQLENYC
|
| description |
INSULIN Insulin family signature. CCTSiCSlyqLenyC
|
| source |
prosite : PS00262
|
|
|
|