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eF-site ID
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1b0a-A |
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PDB Code
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1b0a |
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Chain
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A |
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click to enlarge
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Title
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5,10, METHYLENE-TETRAHYDROPHOLATE DEHYDROGENASE/CYCLOHYDROLASE FROM E COLI. |
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Classification
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OXIDOREDUCTASE,HYDROLASE |
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Compound
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PROTEIN (FOLD BIFUNCTIONAL PROTEIN) |
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Source
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(FOLD_ECOLI) |
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Sequence
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A: |
AAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLV
GSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLE
LIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVD
GFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLN
AVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVE
NADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVV
GDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVE
YHDPQDE
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Description
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Functional site
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1)
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chain |
A |
| residue |
76-101 |
| type |
prosite |
| sequence |
EAELLELIDTLNADNTIDGILVQLPL
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| description |
THF_DHG_CYH_1 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. EaELLelIdtLNaDntidgILVQLPL
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| source |
prosite : PS00766
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2)
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chain |
A |
| residue |
260-268 |
| type |
prosite |
| sequence |
PGGVGPMTV
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| description |
THF_DHG_CYH_2 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. PGGVGPMTV
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| source |
prosite : PS00767
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3)
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chain |
A |
| residue |
166 |
| type |
BINDING |
| sequence |
G
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_01576
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| source |
Swiss-Prot : SWS_FT_FI1
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4)
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chain |
A |
| residue |
232 |
| type |
BINDING |
| sequence |
I
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_01576
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| source |
Swiss-Prot : SWS_FT_FI1
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