eF-site ID 1azy-B PDB Code 1azy Chain B click to enlarge Title STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE Classification GLYCOSYLTRANSFERASE Compound THYMIDINE PHOSPHORYLASE Source ORGANISM_SCIENTIFIC: Escherichia coli; Sequence B:  LFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIA ALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGP IVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHT GGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSL APADKRFYATRDITATVDSIPLITASILAKKLAEGLDALV MDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLT DMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALC VEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQ KGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALG MAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLA VIHAKDENNWQEAAKAVKAAIKLADKAPESTPTVYRRISE Description Functional site 1) chain B residue 84 type sequence K description PHOSPHATE BINDING SITE. source : P4B 2) chain B residue 85 type sequence H description PHOSPHATE BINDING SITE. source : P4B 3) chain B residue 86 type sequence S description PHOSPHATE BINDING SITE. source : P4B 4) chain B residue 95 type sequence S description PHOSPHATE BINDING SITE. source : P4B 5) chain B residue 113 type sequence S description PHOSPHATE BINDING SITE. source : P4B 6) chain B residue 123 type sequence T description PHOSPHATE BINDING SITE. source : P4B 7) chain B residue 171 type sequence R description THYMIDINE BINDING SITE. source : TYB 8) chain B residue 186 type sequence S description THYMIDINE BINDING SITE. source : TYB 9) chain B residue 190 type sequence K description THYMIDINE BINDING SITE. source : TYB 10) chain B residue 86 type catalytic sequence S description 413 source MCSA : MCSA2 11) chain B residue 83 type catalytic sequence D description 413 source MCSA : MCSA2 12) chain B residue 84 type catalytic sequence K description 413 source MCSA : MCSA2 13) chain B residue 85 type catalytic sequence H description 413 source MCSA : MCSA2 14) chain B residue 123 type catalytic sequence T description 413 source MCSA : MCSA2 15) chain B residue 171 type catalytic sequence R description 413 source MCSA : MCSA2 16) chain B residue 186 type catalytic sequence S description 413 source MCSA : MCSA2 17) chain B residue 190 type catalytic sequence K description 413 source MCSA : MCSA2 18) chain B residue 191 type catalytic sequence K description 413 source MCSA : MCSA2

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