|
|
eF-site ID
|
1aya-AP |
|
PDB Code
|
1aya |
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Chain
|
A, P |
|
click to enlarge
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Title
|
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE |
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Classification
|
HYDROLASE(SH2 DOMAIN) |
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Compound
|
PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN) |
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Source
|
null (PGFRB_MOUSE) |
|
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Sequence
|
A: |
MRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFT
LSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYM
EHHGQLKEKNGDVIELKYPLN
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| P: |
SVLXTAVQP
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|
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Description
|
(1) |
TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN) (PTP1D, SHPTP2) (E.C.3.1.3.48) COMPLEXED WITH THE PEPTIDE PDGFR-1009
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Functional site
|
|
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1)
|
chain |
A |
| residue |
66 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine => ECO:0007744|PubMed:18034455
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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2)
|
chain |
P |
| residue |
0 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine; by autocatalysis => ECO:0000250|UniProtKB:P09619
|
| source |
Swiss-Prot : SWS_FT_FI1
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