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eF-site ID
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1axw-AB |
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PDB Code
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1axw |
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Chain
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A, B |
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Title
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E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH METHOTREXATE (MTX) AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP) |
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Classification
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METHYLTRANSFERASE |
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Compound
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THYMIDYLATE SYNTHASE |
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Source
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Escherichia coli (strain K12) (TYSY_ECOLI) |
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Sequence
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A: |
XMKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQ
DGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTI
WDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQL
KNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKL
SCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDF
VWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESI
FDYRFEDFEIEGYDPHPGIKAPVAI
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| B: |
XMKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQ
DGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTI
WDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQL
KNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKL
SCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDF
VWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESI
FDYRFEDFEIEGYDPHPGIKAPVAI
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Description
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