eF-site ID 1axc-C
PDB Code 1axc
Chain C

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Title HUMAN PCNA
Classification COMPLEX (DNA-BINDING PROTEIN/DNA)
Compound PCNA
Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens;
Sequence C:  MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSM
DSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILK
CAGNEDIITLRAEDNADTLALVFEAPEKVSDYEMKLMDLD
VEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISC
AKDGVKFSASGELGNGNIKLSQTEEEAVTIEMNEPVQLTF
ALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHL
KYYLAPKI
Description


Functional site
1) chain C
residue 254
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
source Swiss-Prot : SWS_FT_FI6
2) chain C
residue 77
type MOD_RES
sequence K
description Phosphoserine; by PKC; in vitro => ECO:0000269|PubMed:10753973
source Swiss-Prot : SWS_FT_FI3
3) chain C
residue 80
type MOD_RES
sequence K
description Phosphoserine; by PKC; in vitro => ECO:0000269|PubMed:10753973
source Swiss-Prot : SWS_FT_FI3
4) chain C
residue 248
type MOD_RES
sequence K
description Phosphoserine; by PKC; in vitro => ECO:0000269|PubMed:10753973
source Swiss-Prot : SWS_FT_FI3
5) chain C
residue 211
type MOD_RES
sequence Y
description Phosphotyrosine; by EGFR => ECO:0000269|PubMed:17115032
source Swiss-Prot : SWS_FT_FI4
6) chain C
residue 164
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:17108083, ECO:0000269|PubMed:17130289
source Swiss-Prot : SWS_FT_FI5

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