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eF-site ID
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1axc-A |
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PDB Code
|
1axc |
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Chain
|
A |
|
click to enlarge
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Title
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HUMAN PCNA |
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Classification
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COMPLEX (DNA-BINDING PROTEIN/DNA) |
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Compound
|
PCNA |
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Source
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ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; |
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Sequence
|
A: |
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSM
DSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILK
CAGNEDIITLRAEDNADTLALVFEAPEKVSDYEMKLMDLD
VEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISC
AKDGVKFSASGELGNGNIKLSQTSEEEAVTIEMNEPVQLT
FALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGH
LKYYLAPKI
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
254 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
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| source |
Swiss-Prot : SWS_FT_FI6
|
|
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2)
|
chain |
A |
| residue |
211 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine; by EGFR => ECO:0000269|PubMed:17115032
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| source |
Swiss-Prot : SWS_FT_FI4
|
|
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3)
|
chain |
A |
| residue |
164 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:17108083, ECO:0000269|PubMed:17130289
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
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4)
|
chain |
A |
| residue |
61-79 |
| type |
prosite |
| sequence |
RCDRNLAMGVNLTSMSKIL
|
| description |
PCNA_2 Proliferating cell nuclear antigen signature 2. RCDRnlaMgvnLtSMsKIL
|
| source |
prosite : PS00293
|
|
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5)
|
chain |
A |
| residue |
34-57 |
| type |
prosite |
| sequence |
GVNLQSMDSSHVSLVQLTLRSEGF
|
| description |
PCNA_1 Proliferating cell nuclear antigen signature 1. GVnLqSMDsSHVsLVqLtLrsegF
|
| source |
prosite : PS01251
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