eF-site ID 1axa-B PDB Code 1axa Chain B click to enlarge Title ACTIVE-SITE MOBILITY IN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE AS DEMONSTRATED BY CRYSTAL STRUCTURE OF A28S MUTANT Classification ASPARTYL PROTEASE Compound HIV-1 PROTEASE Source (POL_HV1B1) Sequence B:  PQITLWQRPLVTIKIGGQLKEALLDTGSDDTVLEEMSLPG RWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPT PVNIIGRNLLTQIGCTLNF Description Functional site 1) chain B residue 8 type sequence R description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 2) chain B residue 25 type sequence D description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 3) chain B residue 27 type sequence G description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 4) chain B residue 28 type sequence S description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 5) chain B residue 29 type sequence D description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 6) chain B residue 30 type sequence D description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 7) chain B residue 47 type sequence I description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 8) chain B residue 48 type sequence G description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 9) chain B residue 49 type sequence G description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 10) chain B residue 50 type sequence I description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 11) chain B residue 81 type sequence P description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 12) chain B residue 82 type sequence V description BINDING SITE FOR RESIDUE U0E A 100 source : AC1 13) chain B residue 25 type sequence D description BINDING SITE FOR RESIDUE U0E A 101 source : AC2 14) chain B residue 27 type sequence G description BINDING SITE FOR RESIDUE U0E A 101 source : AC2 15) chain B residue 28 type sequence S description BINDING SITE FOR RESIDUE U0E A 101 source : AC2 16) chain B residue 49 type sequence G description BINDING SITE FOR RESIDUE U0E A 101 source : AC2 17) chain B residue 50 type sequence I description BINDING SITE FOR RESIDUE U0E A 101 source : AC2 18) chain B residue 81 type sequence P description BINDING SITE FOR RESIDUE U0E A 101 source : AC2 19) chain B residue 64 type SITE sequence I description Cleavage; by viral protease => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 20) chain B residue 64 type MOD_RES sequence I description Phosphotyrosine; by host => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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