|
|
eF-site ID
|
1auw-D |
|
PDB Code
|
1auw |
|
Chain
|
D |
|
click to enlarge
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Title
|
H91N DELTA 2 CRYSTALLIN FROM DUCK |
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Classification
|
EYE LENS PROTEIN |
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Compound
|
DELTA 2 CRYSTALLIN |
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Source
|
Anas platyrhynchos (Domestic duck) (Anas boschas) (CRD2_ANAPL) |
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Sequence
|
D: |
TDPIMEKLNSSIAYDQRLSEVDIQGSMAYAKALEKAGILT
KTELEKILSGLEKISEEWSKGVFVVKQSDEDINTANERRL
KELIGDIAGKLHTGRSRNDQVVTDLKLFMKNSLSIISTHL
LQLIKTLVERAAIEIDVILPGYTHLQKAQPIRWSQFLLSH
AVALTRDSERLGEVKKRINVLPLGSGALAGNPLDIDREML
RSELEFASISLNSMDAISERDFVVEFLSFATLLMIHLSKM
AEDLIIYSTSEFGFLTDSDAFSTGSSLMPQKKNPDSLELI
RSKAGRVFGRLASILMVLKGLPSTYNKDLQEDKEAVFDVV
DTLTAVLQVATGVISTLQISKENMEKALTPEMLATDLALY
LVRKGVPFRQAHTASGKAVHLAETKGITINKLSLEDLKSI
SPQFSSDVSQVFNFVNSVEQYTALGGTAKSSVTTQIEQLR
ELMKKQK
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Description
|
|
Functional site
|
|
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1)
|
chain |
D |
| residue |
160 |
| type |
|
| sequence |
H
|
| description |
CATALYTIC HISTIDINE.
|
| source |
: CAD
|
|
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2)
|
chain |
D |
| residue |
160 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Proton acceptor => ECO:0000305|PubMed:11698398
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
D |
| residue |
281 |
| type |
ACT_SITE |
| sequence |
S
|
| description |
Proton donor => ECO:0000305|PubMed:11698398
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
D |
| residue |
27 |
| type |
BINDING |
| sequence |
S
|
| description |
in chain A => ECO:0000269|PubMed:11698398, ECO:0007744|PDB:1K7W
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
D |
| residue |
114 |
| type |
BINDING |
| sequence |
N
|
| description |
in chain A => ECO:0000269|PubMed:11698398, ECO:0007744|PDB:1K7W
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
D |
| residue |
160 |
| type |
catalytic |
| sequence |
H
|
| description |
408
|
| source |
MCSA : MCSA4
|
|
|
7)
|
chain |
D |
| residue |
281 |
| type |
catalytic |
| sequence |
S
|
| description |
408
|
| source |
MCSA : MCSA4
|
|
|
8)
|
chain |
D |
| residue |
287 |
| type |
catalytic |
| sequence |
K
|
| description |
408
|
| source |
MCSA : MCSA4
|
|
|
9)
|
chain |
D |
| residue |
294 |
| type |
catalytic |
| sequence |
E
|
| description |
408
|
| source |
MCSA : MCSA4
|
|
|
10)
|
chain |
D |
| residue |
321 |
| type |
BINDING |
| sequence |
Y
|
| description |
in chain A => ECO:0000269|PubMed:10029536, ECO:0000269|PubMed:11698398, ECO:0007744|PDB:1DCN, ECO:0007744|PDB:1K7W
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
11)
|
chain |
D |
| residue |
329 |
| type |
BINDING |
| sequence |
K
|
| description |
in chain A => ECO:0000269|PubMed:10029536, ECO:0000269|PubMed:11698398, ECO:0007744|PDB:1DCN, ECO:0007744|PDB:1K7W
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
12)
|
chain |
D |
| residue |
326 |
| type |
BINDING |
| sequence |
Q
|
| description |
in chain A => ECO:0000269|PubMed:10029536, ECO:0007744|PDB:1DCN
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
|
13)
|
chain |
D |
| residue |
159 |
| type |
BINDING |
| sequence |
T
|
| description |
in chain C => ECO:0000269|PubMed:10029536, ECO:0000269|PubMed:11698398, ECO:0007744|PDB:1DCN, ECO:0007744|PDB:1K7W
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
14)
|
chain |
D |
| residue |
289 |
| type |
BINDING |
| sequence |
N
|
| description |
in chain B => ECO:0000269|PubMed:10029536, ECO:0000269|PubMed:11698398, ECO:0007744|PDB:1DCN, ECO:0007744|PDB:1K7W
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
15)
|
chain |
D |
| residue |
294 |
| type |
SITE |
| sequence |
E
|
| description |
Increases basicity of active site His => ECO:0000305|PubMed:11698398
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
|
|