|
|
eF-site ID
|
1au1-AB |
|
PDB Code
|
1au1 |
|
Chain
|
A, B |
|
click to enlarge
|
|
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Title
|
HUMAN INTERFERON-BETA CRYSTAL STRUCTURE |
|
Classification
|
INTERFERON |
|
Compound
|
INTERFERON-BETA |
|
Source
|
Homo sapiens (Human) (INB_HUMAN) |
|
|
Sequence
|
A: |
MSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFDI
PEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWN
ETIVENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMSSL
HLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRL
TGYLRN
|
| B: |
MSYNLLGFLQRSSNFQCQKLLWQLNGRCLKDRMNFDIPEE
IKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETI
VENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMSSLHLK
RYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGY
LRN
|
|
|
Description
|
(1) |
INTERFERON-BETA
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
125-143 |
| type |
prosite |
| sequence |
YYGRILHYLKAKEYSHCAW
|
| description |
INTERFERON_A_B_D Interferon alpha, beta and delta family signature. YYgRIlhYLkakeyshCAW
|
| source |
prosite : PS00252
|
|
|
2)
|
chain |
A |
| residue |
80 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:9342320
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
B |
| residue |
80 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:9342320
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
3 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine => ECO:0000250|UniProtKB:P70499
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
B |
| residue |
3 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine => ECO:0000250|UniProtKB:P70499
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|