eF-site ID 1atn-D PDB Code 1atn Chain D click to enlarge Title Atomic structure of the actin:DNASE I complex Classification ENDODEOXYRIBONUCLEASE Compound ACTIN Source ORGANISM_COMMON: rabbit; ORGANISM_SCIENTIFIC: Oryctolagus cuniculus; Sequence D:  LKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQEV RDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERY LFLFRPNKVSVLDTYQYDDGCCGNDSFSREPAVVKFSSHS TKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKWHLND VMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADT TATSTNCAYDRIVVAGSLLQSSVVPGSAAPFDFQAAYGLS NEMALAISDHYPVEVTLT Description (1)  DEOXYRIBONUCLEASE I COMPLEX WITH ACTIN Functional site 1) chain D residue 39 type catalytic sequence E description 41 source MCSA : MCSA1 2) chain D residue 76 type catalytic sequence Y description 41 source MCSA : MCSA1 3) chain D residue 78 type catalytic sequence E description 41 source MCSA : MCSA1 4) chain D residue 134 type catalytic sequence H description 41 source MCSA : MCSA1 5) chain D residue 168 type catalytic sequence D description 41 source MCSA : MCSA1 6) chain D residue 212 type catalytic sequence D description 41 source MCSA : MCSA1 7) chain D residue 252 type catalytic sequence H description 41 source MCSA : MCSA1 8) chain D residue 78 type ACT_SITE sequence E description ACT_SITE => ECO:0000269|PubMed:2395459 source Swiss-Prot : SWS_FT_FI1 9) chain D residue 134 type ACT_SITE sequence H description ACT_SITE => ECO:0000269|PubMed:2395459, ECO:0000269|PubMed:4976790 source Swiss-Prot : SWS_FT_FI2 10) chain D residue 67 type SITE sequence V description Involved in actin-binding => ECO:0000269|PubMed:2395459 source Swiss-Prot : SWS_FT_FI3 11) chain D residue 13 type SITE sequence E description Involved in actin-binding => ECO:0000269|PubMed:2395459 source Swiss-Prot : SWS_FT_FI3 12) chain D residue 65 type SITE sequence Y description Nitration by tetranitromethane destroys a Ca(2+) binding site and inactivates enzyme source Swiss-Prot : SWS_FT_FI4 13) chain D residue 18 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:1748997, ECO:0000269|PubMed:3560229 source Swiss-Prot : SWS_FT_FI5 14) chain D residue 167-174 type prosite sequence GDFNADCS description DNASE_I_2 Deoxyribonuclease I signature 2. GDFNAdCS source prosite : PS00918 15) chain D residue 130-150 type prosite sequence IVALHSAPSDAVAEINSLYDV description DNASE_I_1 Deoxyribonuclease I signature 1. IVALHSAPsdavaEINsLyDV source prosite : PS00919

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