|
|
eF-site ID
|
1ant-L |
|
PDB Code
|
1ant |
|
Chain
|
L |
|
click to enlarge
|
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Title
|
BIOLOGICAL IMPLICATIONS OF A 3 ANGSTROMS STRUCTURE OF DIMERIC ANTITHROMBIN |
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Classification
|
SERINE PROTEASE INHIBITOR |
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Compound
|
ANTITHROMBIN |
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Source
|
Homo sapiens (Human) (ANT3_HUMAN) |
|
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Sequence
|
L: |
DIPMNPMCIYRSATNRRVWELSKANSRFATTFYQHLADSK
NDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDT
ISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDK
SLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWV
SNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFS
PENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVL
ELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDE
LEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSK
LPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVI
AGRSLRPFLVFIREVPLNTIIFMGRVANPCVK
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Description
|
(1) |
ANTITHROMBIN
|
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Functional site
|
|
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1)
|
chain |
L |
| residue |
49 |
| type |
BINDING |
| sequence |
W
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
L |
| residue |
129 |
| type |
BINDING |
| sequence |
R
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
L |
| residue |
145 |
| type |
BINDING |
| sequence |
R
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
L |
| residue |
155 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169, ECO:0000269|Ref.10
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
|
5)
|
chain |
L |
| residue |
192 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16263699, ECO:0000269|PubMed:16335952, ECO:0000269|Ref.10
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
|
6)
|
chain |
L |
| residue |
393 |
| type |
SITE |
| sequence |
R
|
| description |
Reactive bond => ECO:0000269|PubMed:7238875
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
L |
| residue |
96 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218, ECO:0000269|Ref.10
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
8)
|
chain |
L |
| residue |
135 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|Ref.10
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
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