|
|
eF-site ID
|
1afw-B |
|
PDB Code
|
1afw |
|
Chain
|
B |
|
click to enlarge
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Title
|
THE 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE DIMERIC PEROXISOMAL THIOLASE OF SACCHAROMYCES CEREVISIAE |
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Classification
|
THIOLASE |
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Compound
|
3-KETOACETYL-COA THIOLASE |
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Source
|
ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
|
B: |
KNSLLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLY
NFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHR
AACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQI
DIGLALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLI
PMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLF
EDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKD
RGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYID
FQTVGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINE
AFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQ
VATILRELKKDQIGVVSMCIGTGMGAAAIFIKE
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Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
125 |
| type |
|
| sequence |
C
|
| description |
ACTIVE SITE IN CHAIN B.
|
| source |
: AVB
|
|
|
2)
|
chain |
B |
| residue |
375 |
| type |
|
| sequence |
H
|
| description |
ACTIVE SITE IN CHAIN B.
|
| source |
: AVB
|
|
|
3)
|
chain |
B |
| residue |
403 |
| type |
|
| sequence |
C
|
| description |
ACTIVE SITE IN CHAIN B.
|
| source |
: AVB
|
|
|
4)
|
chain |
B |
| residue |
124 |
| type |
|
| sequence |
Q
|
| description |
BINDING SITE FOR RESIDUE MRD B 502
|
| source |
: AC2
|
|
|
5)
|
chain |
B |
| residue |
182 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE MRD B 502
|
| source |
: AC2
|
|
|
6)
|
chain |
B |
| residue |
183 |
| type |
|
| sequence |
L
|
| description |
BINDING SITE FOR RESIDUE MRD B 502
|
| source |
: AC2
|
|
|
7)
|
chain |
B |
| residue |
184 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR RESIDUE MRD B 502
|
| source |
: AC2
|
|
|
8)
|
chain |
B |
| residue |
125 |
| type |
catalytic |
| sequence |
C
|
| description |
77
|
| source |
MCSA : MCSA2
|
|
|
9)
|
chain |
B |
| residue |
375 |
| type |
catalytic |
| sequence |
H
|
| description |
77
|
| source |
MCSA : MCSA2
|
|
|
10)
|
chain |
B |
| residue |
403 |
| type |
catalytic |
| sequence |
C
|
| description |
77
|
| source |
MCSA : MCSA2
|
|
|
11)
|
chain |
B |
| residue |
405 |
| type |
catalytic |
| sequence |
G
|
| description |
77
|
| source |
MCSA : MCSA2
|
|
|
12)
|
chain |
B |
| residue |
125 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Acyl-thioester intermediate
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
13)
|
chain |
B |
| residue |
375 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Proton acceptor
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
14)
|
chain |
B |
| residue |
403 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Proton acceptor
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|