eF-site ID 1adj-ABCD PDB Code 1adj Chain A, B, C, D click to enlarge Title HISTIDYL-TRNA SYNTHETASE IN COMPLEX WITH HISTIDINE Classification COMPLEX (TRNA SYNTHETASE/PEPTIDE) Compound HISTIDYL-TRNA SYNTHETASE Source ORGANISM_SCIENTIFIC: Thermus thermophilus; Sequence A:  TARAVRGTKDLFGKELRMHQRIVATARKVLEAAGALELVT PIFEETQVFEKGVGAATDIVRKEMFTFQDRGGRSLTLRPE GTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQKGRY RQFHQVNYEALGSENPILDAEAVVLLYECLKELGLRRLKV KLSSVGDPEDRARYNAYLREVLSPHREALSEDSKERLEEN PMRILDSKSERDQALLKELGVRPMLDFLGEEARAHLKEVE RHLERLSVPYELEPALVRGLDYYVRTAFEVHHEEIGAQSA LGGGGRYDGLSELLGGPRVPGVGFAFGVERVALALEAEGF GLPEEKGPDLYLIPLTEEAVAEAFYLAEALRPRLRAEYAL APRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLAT GEQVRLSREEVPGYLLQALG B:  TARAVRGTKDLFGKELRMHQRIVATARKVLEAAGALELVT PIFEETQVFEKGVGAATDIVRKEMFTFQDRGGRSLTLRPE GTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQKGRY RQFHQVNYEALGSENPILDAEAVVLLYECLKELGLRRLKV KLSSVGDPEDRARYNAYLREVLSPHREALSEDSKERLEEN PMRILDSKSERDQALLKELGVRPMLDFLGEEARAHLKEVE RHLERLSVPYELEPALVRGLDYYVRTAFEVHHEEIGAQSA LGGGGRYDGLSELLGGPRVPGVGFAFGVERVALALEAEGF GLPEEKGPDLYLIPLTEEAVAEAFYLAEALRPRLRAEYAL APRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLAT GEQVRLSREEVPGYLLQALG C:  TARAVRGTKDLFGKELRMHQRIVATARKVLEAAGALELVT PIFEETQVFEKGVGAATDIVRKEMFTFQDRGGRSLTLRPE GTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQKGRY RQFHQVNYEALGSENPILDAEAVVLLYECLKELGLRRLKV KLSSVGDPEDRARYNAYLREVLSPHREALSEDSKERLEEN PMRILDSKSERDQALLKELGVRPMLDFLGEEARAHLKEVE RHLERLSVPYELEPALVRGLDYYVRTAFEVHHEEIGAQSA LGGGGRYDGLSELLGGPRVPGVGFAFGVERVALALEAEGF GLPEEKGPDLYLIPLTEEAVAEAFYLAEALRPRLRAEYAL APRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLAT GEQVRLSREEVPGYLLQALG D:  TARAVRGTKDLFGKELRMHQRIVATARKVLEAAGALELVT PIFEETQVFEKGVGAATDIVRKEMFTFQDRGGRSLTLRPE GTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQKGRY RQFHQVNYEALGSENPILDAEAVVLLYECLKELGLRRLKV KLSSVGDPEDRARYNAYLREVLSPHREALSEDSKERLEEN PMRILDSKSERDQALLKELGVRPMLDFLGEEARAHLKEVE RHLERLSVPYELEPALVRGLDYYVRTAFEVHHEEIGAQSA LGGGGRYDGLSELLGGPRVPGVGFAFGVERVALALEAEGF GLPEEKGPDLYLIPLTEEAVAEAFYLAEALRPRLRAEYAL APRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLAT GEQVRLSREEVPGYLLQALG Description Functional site 1) chain A residue 18 type sequence R description BINDING SITE FOR RESIDUE SO4 A 422 source : AC1 2) chain A residue 22 type sequence R description BINDING SITE FOR RESIDUE SO4 A 422 source : AC1 3) chain D residue 18 type sequence R description BINDING SITE FOR RESIDUE SO4 D 422 source : AC2 4) chain D residue 22 type sequence R description BINDING SITE FOR RESIDUE SO4 D 422 source : AC2 5) chain C residue 18 type sequence R description BINDING SITE FOR RESIDUE SO4 C 422 source : AC3 6) chain C residue 22 type sequence R description BINDING SITE FOR RESIDUE SO4 C 422 source : AC3 7) chain B residue 18 type sequence R description BINDING SITE FOR RESIDUE SO4 B 422 source : AC4 8) chain B residue 22 type sequence R description BINDING SITE FOR RESIDUE SO4 B 422 source : AC4 9) chain A residue 81 type sequence E description BINDING SITE FOR RESIDUE HIS A 423 source : AC5 10) chain A residue 83 type sequence T description BINDING SITE FOR RESIDUE HIS A 423 source : AC5 11) chain A residue 130 type sequence E description BINDING SITE FOR RESIDUE HIS A 423 source : AC5 12) chain A residue 259 type sequence R description BINDING SITE FOR RESIDUE HIS A 423 source : AC5 13) chain A residue 263 type sequence Y description BINDING SITE FOR RESIDUE HIS A 423 source : AC5 14) chain A residue 264 type sequence Y description BINDING SITE FOR RESIDUE HIS A 423 source : AC5 15) chain A residue 286 type sequence G description BINDING SITE FOR RESIDUE HIS A 423 source : AC5 16) chain A residue 288 type sequence Y description BINDING SITE FOR RESIDUE HIS A 423 source : AC5 17) chain A residue 304 type sequence G description BINDING SITE FOR RESIDUE HIS A 423 source : AC5 18) chain A residue 305 type sequence F description BINDING SITE FOR RESIDUE HIS A 423 source : AC5 19) chain A residue 306 type sequence A description BINDING SITE FOR RESIDUE HIS A 423 source : AC5 20) chain B residue 81 type sequence E description BINDING SITE FOR RESIDUE HIS B 423 source : AC6 21) chain B residue 83 type sequence T description BINDING SITE FOR RESIDUE HIS B 423 source : AC6 22) chain B residue 128 type sequence N description BINDING SITE FOR RESIDUE HIS B 423 source : AC6 23) chain B residue 130 type sequence E description BINDING SITE FOR RESIDUE HIS B 423 source : AC6 24) chain B residue 263 type sequence Y description BINDING SITE FOR RESIDUE HIS B 423 source : AC6 25) chain B residue 264 type sequence Y description BINDING SITE FOR RESIDUE HIS B 423 source : AC6 26) chain B residue 304 type sequence G description BINDING SITE FOR RESIDUE HIS B 423 source : AC6 27) chain B residue 305 type sequence F description BINDING SITE FOR RESIDUE HIS B 423 source : AC6 28) chain B residue 306 type sequence A description BINDING SITE FOR RESIDUE HIS B 423 source : AC6 29) chain C residue 81 type sequence E description BINDING SITE FOR RESIDUE HIS C 423 source : AC7 30) chain C residue 83 type sequence T description BINDING SITE FOR RESIDUE HIS C 423 source : AC7 31) chain C residue 126 type sequence Q description BINDING SITE FOR RESIDUE HIS C 423 source : AC7 32) chain C residue 130 type sequence E description BINDING SITE FOR RESIDUE HIS C 423 source : AC7 33) chain C residue 263 type sequence Y description BINDING SITE FOR RESIDUE HIS C 423 source : AC7 34) chain C residue 264 type sequence Y description BINDING SITE FOR RESIDUE HIS C 423 source : AC7 35) chain C residue 286 type sequence G description BINDING SITE FOR RESIDUE HIS C 423 source : AC7 36) chain C residue 288 type sequence Y description BINDING SITE FOR RESIDUE HIS C 423 source : AC7 37) chain C residue 304 type sequence G description BINDING SITE FOR RESIDUE HIS C 423 source : AC7 38) chain C residue 305 type sequence F description BINDING SITE FOR RESIDUE HIS C 423 source : AC7 39) chain C residue 306 type sequence A description BINDING SITE FOR RESIDUE HIS C 423 source : AC7 40) chain D residue 81 type sequence E description BINDING SITE FOR RESIDUE HIS D 423 source : AC8 41) chain D residue 83 type sequence T description BINDING SITE FOR RESIDUE HIS D 423 source : AC8 42) chain D residue 126 type sequence Q description BINDING SITE FOR RESIDUE HIS D 423 source : AC8 43) chain D residue 130 type sequence E description BINDING SITE FOR RESIDUE HIS D 423 source : AC8 44) chain D residue 263 type sequence Y description BINDING SITE FOR RESIDUE HIS D 423 source : AC8 45) chain D residue 264 type sequence Y description BINDING SITE FOR RESIDUE HIS D 423 source : AC8 46) chain D residue 285 type sequence G description BINDING SITE FOR RESIDUE HIS D 423 source : AC8 47) chain D residue 286 type sequence G description BINDING SITE FOR RESIDUE HIS D 423 source : AC8 48) chain D residue 288 type sequence Y description BINDING SITE FOR RESIDUE HIS D 423 source : AC8 49) chain D residue 304 type sequence G description BINDING SITE FOR RESIDUE HIS D 423 source : AC8 50) chain D residue 305 type sequence F description BINDING SITE FOR RESIDUE HIS D 423 source : AC8

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