eF-site/Summary 1adb-B

eF-site ID	1adb-B
PDB Code	1adb
Chain	B

click to enlarge

Title	CRYSTALLOGRAPHIC STUDIES OF ISOSTERIC NAD ANALOGUES BOUND TO ALCOHOL DEHYDROGENASE: SPECIFICITY AND SUBSTRATE BINDING IN TWO TERNARY COMPLEXES
Classification	OXIDOREDUCTASE (NAD(A)-CHOH(D))
Compound	ALCOHOL DEHYDROGENASE
Source	Equus caballus (Horse) (ADHE_HORSE)

Sequence	B:	STAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKM VATGICRSDDHVVSGTLVTPLPVIAGHEAAGIVESIGEGV TTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMPR GTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKI DAASPLEKVCLIGCGFSTGYGSAVKVAKVTQGSTCAVFGL GGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATEC VNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALS CCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGRTWKGAIFG GFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFD LLRSGESIRTILTF

Description

Functional site


1)	chain	B
	residue	46
	type
	sequence	C
	description
	source	: DMB

2)	chain	B
	residue	48
	type
	sequence	S
	description
	source	: DMB

3)	chain	B
	residue	67
	type
	sequence	H
	description
	source	: DMB

4)	chain	B
	residue	93
	type
	sequence	F
	description
	source	: DMB

5)	chain	B
	residue	141
	type
	sequence	L
	description
	source	: DMB

6)	chain	B
	residue	174
	type
	sequence	C
	description
	source	: DMB

7)	chain	B
	residue	1
	type
	sequence	S
	description
	source	: DMB

8)	chain	B
	residue	3
	type
	sequence	A
	description
	source	: DMB

9)	chain	B
	residue	47
	type
	sequence	R
	description
	source	: NAB

10)	chain	B
	residue	51
	type
	sequence	H
	description
	source	: NAB

11)	chain	B
	residue	178
	type
	sequence	T
	description
	source	: NAB

12)	chain	B
	residue	198
	type
	sequence	F
	description
	source	: NAB

13)	chain	B
	residue	199
	type
	sequence	G
	description
	source	: NAB

14)	chain	B
	residue	200
	type
	sequence	L
	description
	source	: NAB

15)	chain	B
	residue	202
	type
	sequence	G
	description
	source	: NAB

16)	chain	B
	residue	203
	type
	sequence	V
	description
	source	: NAB

17)	chain	B
	residue	222
	type
	sequence	V
	description
	source	: NAB

18)	chain	B
	residue	223
	type
	sequence	D
	description
	source	: NAB

19)	chain	B
	residue	224
	type
	sequence	I
	description
	source	: NAB

20)	chain	B
	residue	228
	type
	sequence	K
	description
	source	: NAB

21)	chain	B
	residue	269
	type
	sequence	I
	description
	source	: NAB

22)	chain	B
	residue	270
	type
	sequence	G
	description
	source	: NAB

23)	chain	B
	residue	271
	type
	sequence	R
	description
	source	: NAB

24)	chain	B
	residue	292
	type
	sequence	V
	description
	source	: NAB

25)	chain	B
	residue	293
	type
	sequence	G
	description
	source	: NAB

26)	chain	B
	residue	294
	type
	sequence	V
	description
	source	: NAB

27)	chain	B
	residue	319
	type
	sequence	F
	description
	source	: NAB

28)	chain	B
	residue	369
	type
	sequence	R
	description
	source	: NAB

29)	chain	B
	residue	46
	type
	sequence	C
	description	BINDING SITE FOR RESIDUE ZN B 375
	source	: AC3

30)	chain	B
	residue	48
	type
	sequence	S
	description	BINDING SITE FOR RESIDUE ZN B 375
	source	: AC3

31)	chain	B
	residue	67
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE ZN B 375
	source	: AC3

32)	chain	B
	residue	174
	type
	sequence	C
	description	BINDING SITE FOR RESIDUE ZN B 375
	source	: AC3

33)	chain	B
	residue	97
	type
	sequence	C
	description	BINDING SITE FOR RESIDUE ZN B 376
	source	: AC4

34)	chain	B
	residue	100
	type
	sequence	C
	description	BINDING SITE FOR RESIDUE ZN B 376
	source	: AC4

35)	chain	B
	residue	103
	type
	sequence	C
	description	BINDING SITE FOR RESIDUE ZN B 376
	source	: AC4

36)	chain	B
	residue	111
	type
	sequence	C
	description	BINDING SITE FOR RESIDUE ZN B 376
	source	: AC4

37)	chain	B
	residue	46
	type
	sequence	C
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

38)	chain	B
	residue	47
	type
	sequence	R
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

39)	chain	B
	residue	48
	type
	sequence	S
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

40)	chain	B
	residue	51
	type
	sequence	H
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

41)	chain	B
	residue	174
	type
	sequence	C
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

42)	chain	B
	residue	201
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

43)	chain	B
	residue	202
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

44)	chain	B
	residue	203
	type
	sequence	V
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

45)	chain	B
	residue	223
	type
	sequence	D
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

46)	chain	B
	residue	224
	type
	sequence	I
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

47)	chain	B
	residue	228
	type
	sequence	K
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

48)	chain	B
	residue	268
	type
	sequence	V
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

49)	chain	B
	residue	269
	type
	sequence	I
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

50)	chain	B
	residue	271
	type
	sequence	R
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

51)	chain	B
	residue	292
	type
	sequence	V
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

52)	chain	B
	residue	293
	type
	sequence	G
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

53)	chain	B
	residue	294
	type
	sequence	V
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

54)	chain	B
	residue	317
	type
	sequence	A
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

55)	chain	B
	residue	318
	type
	sequence	I
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

56)	chain	B
	residue	319
	type
	sequence	F
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

57)	chain	B
	residue	369
	type
	sequence	R
	description	BINDING SITE FOR RESIDUE CND B 377
	source	: AC6

58)	chain	B
	residue	48
	type
	sequence	S
	description	BINDING SITE FOR RESIDUE EOH B 378
	source	: AC8

59)	chain	B
	residue	294
	type
	sequence	V
	description	BINDING SITE FOR RESIDUE EOH B 378
	source	: AC8

60)	chain	B
	residue	47
	type	catalytic
	sequence	R
	description	256
	source	MCSA : MCSA2

61)	chain	B
	residue	49
	type	catalytic
	sequence	D
	description	256
	source	MCSA : MCSA2

62)	chain	B
	residue	52
	type	catalytic
	sequence	V
	description	256
	source	MCSA : MCSA2

63)	chain	B
	residue	68
	type	catalytic
	sequence	E
	description	256
	source	MCSA : MCSA2

64)	chain	B
	residue	175
	type	catalytic
	sequence	G
	description	256
	source	MCSA : MCSA2

65)	chain	B
	residue	229
	type	BINDING
	sequence	F
	description	BINDING => ECO:0000269\|PubMed:15299346, ECO:0007744\|PDB:1A71, ECO:0007744\|PDB:1ADB, ECO:0007744\|PDB:1AXE, ECO:0007744\|PDB:1AXG, ECO:0007744\|PDB:1BTO, ECO:0007744\|PDB:1HET, ECO:0007744\|PDB:1HEU, ECO:0007744\|PDB:1HF3, ECO:0007744\|PDB:1HLD, ECO:0007744\|PDB:1JU9, ECO:0007744\|PDB:1LDE, ECO:0007744\|PDB:1MGO, ECO:0007744\|PDB:1N8K, ECO:0007744\|PDB:1N92, ECO:0007744\|PDB:1QLH, ECO:0007744\|PDB:2JHF, ECO:0007744\|PDB:2JHG, ECO:0007744\|PDB:2OHX, ECO:0007744\|PDB:2OXI, ECO:0007744\|PDB:3OQ6, ECO:0007744\|PDB:4DWV, ECO:0007744\|PDB:4DXH, ECO:0007744\|PDB:4NFH, ECO:0007744\|PDB:4NFS, ECO:0007744\|PDB:4NG5, ECO:0007744\|PDB:4XD2, ECO:0007744\|PDB:5ADH, ECO:0007744\|PDB:6ADH
	source	Swiss-Prot : SWS_FT_FI7

66)	chain	B
	residue	47
	type	BINDING
	sequence	R
	description	BINDING => ECO:0000269\|PubMed:15299346, ECO:0000269\|PubMed:178875, ECO:0007744\|PDB:1A71, ECO:0007744\|PDB:1A72, ECO:0007744\|PDB:1ADB, ECO:0007744\|PDB:1ADC, ECO:0007744\|PDB:1ADF, ECO:0007744\|PDB:1ADG, ECO:0007744\|PDB:1AXE, ECO:0007744\|PDB:1AXG, ECO:0007744\|PDB:1BTO, ECO:0007744\|PDB:1HET, ECO:0007744\|PDB:1HLD, ECO:0007744\|PDB:1JU9, ECO:0007744\|PDB:1LDE, ECO:0007744\|PDB:1LDY, ECO:0007744\|PDB:1MG0, ECO:0007744\|PDB:1MGO, ECO:0007744\|PDB:1N8K, ECO:0007744\|PDB:1N92, ECO:0007744\|PDB:1P1R, ECO:0007744\|PDB:1QLH, ECO:0007744\|PDB:1QLJ, ECO:0007744\|PDB:1QV6, ECO:0007744\|PDB:1QV7, ECO:0007744\|PDB:1YE3, ECO:0007744\|PDB:2JHG, ECO:0007744\|PDB:2OHX, ECO:0007744\|PDB:3BTO, ECO:0007744\|PDB:3OQ6, ECO:0007744\|PDB:4DWV, ECO:0007744\|PDB:4DXH, ECO:0007744\|PDB:4NFH, ECO:0007744\|PDB:4NFS, ECO:0007744\|PDB:4NG5, ECO:0007744\|PDB:4XD2, ECO:0007744\|PDB:5ADH, ECO:0007744\|PDB:6ADH, ECO:0007744\|PDB:7ADH, ECO:0007744\|PDB:8ADH
	source	Swiss-Prot : SWS_FT_FI1

67)	chain	B
	residue	68
	type	BINDING
	sequence	E
	description	BINDING => ECO:0000269\|PubMed:15299346, ECO:0000269\|PubMed:178875, ECO:0007744\|PDB:1A71, ECO:0007744\|PDB:1A72, ECO:0007744\|PDB:1ADB, ECO:0007744\|PDB:1ADC, ECO:0007744\|PDB:1ADF, ECO:0007744\|PDB:1ADG, ECO:0007744\|PDB:1AXE, ECO:0007744\|PDB:1AXG, ECO:0007744\|PDB:1BTO, ECO:0007744\|PDB:1HET, ECO:0007744\|PDB:1HLD, ECO:0007744\|PDB:1JU9, ECO:0007744\|PDB:1LDE, ECO:0007744\|PDB:1LDY, ECO:0007744\|PDB:1MG0, ECO:0007744\|PDB:1MGO, ECO:0007744\|PDB:1N8K, ECO:0007744\|PDB:1N92, ECO:0007744\|PDB:1P1R, ECO:0007744\|PDB:1QLH, ECO:0007744\|PDB:1QLJ, ECO:0007744\|PDB:1QV6, ECO:0007744\|PDB:1QV7, ECO:0007744\|PDB:1YE3, ECO:0007744\|PDB:2JHG, ECO:0007744\|PDB:2OHX, ECO:0007744\|PDB:3BTO, ECO:0007744\|PDB:3OQ6, ECO:0007744\|PDB:4DWV, ECO:0007744\|PDB:4DXH, ECO:0007744\|PDB:4NFH, ECO:0007744\|PDB:4NFS, ECO:0007744\|PDB:4NG5, ECO:0007744\|PDB:4XD2, ECO:0007744\|PDB:5ADH, ECO:0007744\|PDB:6ADH, ECO:0007744\|PDB:7ADH, ECO:0007744\|PDB:8ADH
	source	Swiss-Prot : SWS_FT_FI1

68)	chain	B
	residue	98
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:15299346, ECO:0000269\|PubMed:178875, ECO:0007744\|PDB:1A71, ECO:0007744\|PDB:1A72, ECO:0007744\|PDB:1ADB, ECO:0007744\|PDB:1ADC, ECO:0007744\|PDB:1ADF, ECO:0007744\|PDB:1ADG, ECO:0007744\|PDB:1AXE, ECO:0007744\|PDB:1AXG, ECO:0007744\|PDB:1BTO, ECO:0007744\|PDB:1HET, ECO:0007744\|PDB:1HLD, ECO:0007744\|PDB:1JU9, ECO:0007744\|PDB:1LDE, ECO:0007744\|PDB:1LDY, ECO:0007744\|PDB:1MG0, ECO:0007744\|PDB:1MGO, ECO:0007744\|PDB:1N8K, ECO:0007744\|PDB:1N92, ECO:0007744\|PDB:1P1R, ECO:0007744\|PDB:1QLH, ECO:0007744\|PDB:1QLJ, ECO:0007744\|PDB:1QV6, ECO:0007744\|PDB:1QV7, ECO:0007744\|PDB:1YE3, ECO:0007744\|PDB:2JHG, ECO:0007744\|PDB:2OHX, ECO:0007744\|PDB:2OXI, ECO:0007744\|PDB:3BTO, ECO:0007744\|PDB:3OQ6, ECO:0007744\|PDB:4DWV, ECO:0007744\|PDB:4DXH, ECO:0007744\|PDB:4NFH, ECO:0007744\|PDB:4NFS, ECO:0007744\|PDB:4NG5, ECO:0007744\|PDB:4XD2, ECO:0007744\|PDB:5ADH, ECO:0007744\|PDB:6ADH, ECO:0007744\|PDB:7ADH, ECO:0007744\|PDB:8ADH
	source	Swiss-Prot : SWS_FT_FI3

69)	chain	B
	residue	101
	type	BINDING
	sequence	R
	description	BINDING => ECO:0000269\|PubMed:15299346, ECO:0000269\|PubMed:178875, ECO:0007744\|PDB:1A71, ECO:0007744\|PDB:1A72, ECO:0007744\|PDB:1ADB, ECO:0007744\|PDB:1ADC, ECO:0007744\|PDB:1ADF, ECO:0007744\|PDB:1ADG, ECO:0007744\|PDB:1AXE, ECO:0007744\|PDB:1AXG, ECO:0007744\|PDB:1BTO, ECO:0007744\|PDB:1HET, ECO:0007744\|PDB:1HLD, ECO:0007744\|PDB:1JU9, ECO:0007744\|PDB:1LDE, ECO:0007744\|PDB:1LDY, ECO:0007744\|PDB:1MG0, ECO:0007744\|PDB:1MGO, ECO:0007744\|PDB:1N8K, ECO:0007744\|PDB:1N92, ECO:0007744\|PDB:1P1R, ECO:0007744\|PDB:1QLH, ECO:0007744\|PDB:1QLJ, ECO:0007744\|PDB:1QV6, ECO:0007744\|PDB:1QV7, ECO:0007744\|PDB:1YE3, ECO:0007744\|PDB:2JHG, ECO:0007744\|PDB:2OHX, ECO:0007744\|PDB:2OXI, ECO:0007744\|PDB:3BTO, ECO:0007744\|PDB:3OQ6, ECO:0007744\|PDB:4DWV, ECO:0007744\|PDB:4DXH, ECO:0007744\|PDB:4NFH, ECO:0007744\|PDB:4NFS, ECO:0007744\|PDB:4NG5, ECO:0007744\|PDB:4XD2, ECO:0007744\|PDB:5ADH, ECO:0007744\|PDB:6ADH, ECO:0007744\|PDB:7ADH, ECO:0007744\|PDB:8ADH
	source	Swiss-Prot : SWS_FT_FI3

70)	chain	B
	residue	104
	type	BINDING
	sequence	K
	description	BINDING => ECO:0000269\|PubMed:15299346, ECO:0000269\|PubMed:178875, ECO:0007744\|PDB:1A71, ECO:0007744\|PDB:1A72, ECO:0007744\|PDB:1ADB, ECO:0007744\|PDB:1ADC, ECO:0007744\|PDB:1ADF, ECO:0007744\|PDB:1ADG, ECO:0007744\|PDB:1AXE, ECO:0007744\|PDB:1AXG, ECO:0007744\|PDB:1BTO, ECO:0007744\|PDB:1HET, ECO:0007744\|PDB:1HLD, ECO:0007744\|PDB:1JU9, ECO:0007744\|PDB:1LDE, ECO:0007744\|PDB:1LDY, ECO:0007744\|PDB:1MG0, ECO:0007744\|PDB:1MGO, ECO:0007744\|PDB:1N8K, ECO:0007744\|PDB:1N92, ECO:0007744\|PDB:1P1R, ECO:0007744\|PDB:1QLH, ECO:0007744\|PDB:1QLJ, ECO:0007744\|PDB:1QV6, ECO:0007744\|PDB:1QV7, ECO:0007744\|PDB:1YE3, ECO:0007744\|PDB:2JHG, ECO:0007744\|PDB:2OHX, ECO:0007744\|PDB:2OXI, ECO:0007744\|PDB:3BTO, ECO:0007744\|PDB:3OQ6, ECO:0007744\|PDB:4DWV, ECO:0007744\|PDB:4DXH, ECO:0007744\|PDB:4NFH, ECO:0007744\|PDB:4NFS, ECO:0007744\|PDB:4NG5, ECO:0007744\|PDB:4XD2, ECO:0007744\|PDB:5ADH, ECO:0007744\|PDB:6ADH, ECO:0007744\|PDB:7ADH, ECO:0007744\|PDB:8ADH
	source	Swiss-Prot : SWS_FT_FI3

71)	chain	B
	residue	112
	type	BINDING
	sequence	L
	description	BINDING => ECO:0000269\|PubMed:15299346, ECO:0000269\|PubMed:178875, ECO:0007744\|PDB:1A71, ECO:0007744\|PDB:1A72, ECO:0007744\|PDB:1ADB, ECO:0007744\|PDB:1ADC, ECO:0007744\|PDB:1ADF, ECO:0007744\|PDB:1ADG, ECO:0007744\|PDB:1AXE, ECO:0007744\|PDB:1AXG, ECO:0007744\|PDB:1BTO, ECO:0007744\|PDB:1HET, ECO:0007744\|PDB:1HLD, ECO:0007744\|PDB:1JU9, ECO:0007744\|PDB:1LDE, ECO:0007744\|PDB:1LDY, ECO:0007744\|PDB:1MG0, ECO:0007744\|PDB:1MGO, ECO:0007744\|PDB:1N8K, ECO:0007744\|PDB:1N92, ECO:0007744\|PDB:1P1R, ECO:0007744\|PDB:1QLH, ECO:0007744\|PDB:1QLJ, ECO:0007744\|PDB:1QV6, ECO:0007744\|PDB:1QV7, ECO:0007744\|PDB:1YE3, ECO:0007744\|PDB:2JHG, ECO:0007744\|PDB:2OHX, ECO:0007744\|PDB:2OXI, ECO:0007744\|PDB:3BTO, ECO:0007744\|PDB:3OQ6, ECO:0007744\|PDB:4DWV, ECO:0007744\|PDB:4DXH, ECO:0007744\|PDB:4NFH, ECO:0007744\|PDB:4NFS, ECO:0007744\|PDB:4NG5, ECO:0007744\|PDB:4XD2, ECO:0007744\|PDB:5ADH, ECO:0007744\|PDB:6ADH, ECO:0007744\|PDB:7ADH, ECO:0007744\|PDB:8ADH
	source	Swiss-Prot : SWS_FT_FI3

72)	chain	B
	residue	200
	type	BINDING
	sequence	L
	description	BINDING => ECO:0000269\|PubMed:15299346, ECO:0007744\|PDB:1ADB, ECO:0007744\|PDB:1AXE, ECO:0007744\|PDB:1BTO, ECO:0007744\|PDB:1HET, ECO:0007744\|PDB:1HEU, ECO:0007744\|PDB:1HF3, ECO:0007744\|PDB:1HLD, ECO:0007744\|PDB:1JU9, ECO:0007744\|PDB:1LDE, ECO:0007744\|PDB:1LDY, ECO:0007744\|PDB:1MG0, ECO:0007744\|PDB:1MGO, ECO:0007744\|PDB:1N8K, ECO:0007744\|PDB:1N92, ECO:0007744\|PDB:1P1R, ECO:0007744\|PDB:1QV6, ECO:0007744\|PDB:1QV7, ECO:0007744\|PDB:2JHF, ECO:0007744\|PDB:2JHG, ECO:0007744\|PDB:2OHX, ECO:0007744\|PDB:2OXI, ECO:0007744\|PDB:3BTO, ECO:0007744\|PDB:3OQ6, ECO:0007744\|PDB:4DWV, ECO:0007744\|PDB:4DXH, ECO:0007744\|PDB:4NFH, ECO:0007744\|PDB:4XD2, ECO:0007744\|PDB:6ADH
	source	Swiss-Prot : SWS_FT_FI5

73)	chain	B
	residue	224
	type	BINDING
	sequence	I
	description	BINDING => ECO:0000269\|PubMed:15299346, ECO:0007744\|PDB:1A71, ECO:0007744\|PDB:1ADB, ECO:0007744\|PDB:1AXE, ECO:0007744\|PDB:1AXG, ECO:0007744\|PDB:1BTO, ECO:0007744\|PDB:1HET, ECO:0007744\|PDB:1HEU, ECO:0007744\|PDB:1HF3, ECO:0007744\|PDB:1HLD, ECO:0007744\|PDB:1JU9, ECO:0007744\|PDB:1LDE, ECO:0007744\|PDB:1LDY, ECO:0007744\|PDB:1MG0, ECO:0007744\|PDB:1MGO, ECO:0007744\|PDB:1N8K, ECO:0007744\|PDB:1N92, ECO:0007744\|PDB:1P1R, ECO:0007744\|PDB:1QLH, ECO:0007744\|PDB:1QV6, ECO:0007744\|PDB:1QV7, ECO:0007744\|PDB:2JHF, ECO:0007744\|PDB:2JHG, ECO:0007744\|PDB:2OHX, ECO:0007744\|PDB:2OXI, ECO:0007744\|PDB:3BTO, ECO:0007744\|PDB:3OQ6, ECO:0007744\|PDB:4DWV, ECO:0007744\|PDB:4DXH, ECO:0007744\|PDB:4NFH, ECO:0007744\|PDB:4NFS, ECO:0007744\|PDB:4NG5, ECO:0007744\|PDB:4XD2, ECO:0007744\|PDB:5ADH, ECO:0007744\|PDB:6ADH
	source	Swiss-Prot : SWS_FT_FI6

74)	chain	B
	residue	2
	type	MOD_RES
	sequence	T
	description	N-acetylserine => ECO:0000269\|PubMed:5466062
	source	Swiss-Prot : SWS_FT_FI9

75)	chain	B
	residue	49
	type	BINDING
	sequence	D
	description	BINDING => ECO:0000250\|UniProtKB:P06525
	source	Swiss-Prot : SWS_FT_FI2

76)	chain	B
	residue	293
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000250\|UniProtKB:P06525
	source	Swiss-Prot : SWS_FT_FI2

77)	chain	B
	residue	320
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000250\|UniProtKB:P06525
	source	Swiss-Prot : SWS_FT_FI2

78)	chain	B
	residue	175
	type	BINDING
	sequence	G
	description	BINDING => ECO:0000269\|PubMed:15299346, ECO:0007744\|PDB:1A71, ECO:0007744\|PDB:1A72, ECO:0007744\|PDB:1ADB, ECO:0007744\|PDB:1ADC, ECO:0007744\|PDB:1ADF, ECO:0007744\|PDB:1ADG, ECO:0007744\|PDB:1AXE, ECO:0007744\|PDB:1AXG, ECO:0007744\|PDB:1BTO, ECO:0007744\|PDB:1HET, ECO:0007744\|PDB:1HLD, ECO:0007744\|PDB:1JU9, ECO:0007744\|PDB:1LDE, ECO:0007744\|PDB:1LDY, ECO:0007744\|PDB:1MG0, ECO:0007744\|PDB:1MGO, ECO:0007744\|PDB:1N8K, ECO:0007744\|PDB:1N92, ECO:0007744\|PDB:1P1R, ECO:0007744\|PDB:1QLH, ECO:0007744\|PDB:1QLJ, ECO:0007744\|PDB:1QV6, ECO:0007744\|PDB:1QV7, ECO:0007744\|PDB:1YE3, ECO:0007744\|PDB:2JHG, ECO:0007744\|PDB:2OHX, ECO:0007744\|PDB:3BTO, ECO:0007744\|PDB:3OQ6, ECO:0007744\|PDB:4DWV, ECO:0007744\|PDB:4DXH, ECO:0007744\|PDB:4NFH, ECO:0007744\|PDB:4NFS, ECO:0007744\|PDB:4NG5, ECO:0007744\|PDB:4XD2, ECO:0007744\|PDB:5ADH, ECO:0007744\|PDB:6ADH, ECO:0007744\|PDB:7ADH, ECO:0007744\|PDB:8ADH
	source	Swiss-Prot : SWS_FT_FI4

79)	chain	B
	residue	370
	type	BINDING
	sequence	T
	description	BINDING => ECO:0000269\|PubMed:15299346, ECO:0007744\|PDB:1A71, ECO:0007744\|PDB:1ADB, ECO:0007744\|PDB:1AXE, ECO:0007744\|PDB:1AXG, ECO:0007744\|PDB:1BTO, ECO:0007744\|PDB:1HET, ECO:0007744\|PDB:1HEU, ECO:0007744\|PDB:1HF3, ECO:0007744\|PDB:1HLD, ECO:0007744\|PDB:1LDE, ECO:0007744\|PDB:1LDY, ECO:0007744\|PDB:1MG0, ECO:0007744\|PDB:1MGO, ECO:0007744\|PDB:1N8K, ECO:0007744\|PDB:1N92, ECO:0007744\|PDB:1P1R, ECO:0007744\|PDB:1QV6, ECO:0007744\|PDB:1QV7, ECO:0007744\|PDB:2JHF, ECO:0007744\|PDB:2JHG, ECO:0007744\|PDB:2OHX, ECO:0007744\|PDB:2OXI, ECO:0007744\|PDB:3BTO, ECO:0007744\|PDB:3OQ6, ECO:0007744\|PDB:4DWV, ECO:0007744\|PDB:4DXH, ECO:0007744\|PDB:4NFH, ECO:0007744\|PDB:4NFS, ECO:0007744\|PDB:4NG5, ECO:0007744\|PDB:4XD2, ECO:0007744\|PDB:6ADH
	source	Swiss-Prot : SWS_FT_FI8