eF-site ID 1ad3-A PDB Code 1ad3 Chain A click to enlarge Title CLASS 3 ALDEHYDE DEHYDROGENASE COMPLEX WITH NICOTINAMIDE-ADENINE-DINUCLEOTIDE Classification OXIDOREDUCTASE Compound ALDEHYDE DEHYDROGENASE (CLASS 3) Source null (AL3A1_RAT) Sequence A:  SISDTVKRAREAFNSGKTRSLQFRIQQLEALQRMINENLK SISGALASDLGKNEWTSYYEEVAHVLEELDTTIKELPDWA EDEPVAKTRQTQQDDLYIHSEPLGVVLVIGAWNYPFNLTI QPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQYMDQNL YLVVKGGVPETTELLKERFDHIMYTGSTAVGKIVMAAAAK HLTPVTLELGGKSPCYVDKDCDLDVACRRIAWGKFMNSGQ TCVAPDYILCDPSIQNQIVEKLKKSLKDFYGEDAKQSRDY GRIINDRHFQRVKGLIDNQKVAHGGTWDQSSRYIAPTILV DVDPQSPVMQEEIFGPVMPIVCVRSLEEAIQFINQREKPL ALYVFSNNEKVIKKMIAETSSGGVTANDVIVHITVPTLPF GGVGNSGMGAYHGKKSFETFSHRRSCLVKSLLNEEAHKAR YPPSPA Description Functional site 1) chain A residue 216 type sequence C description CATALYTIC CYSTEINE source : CTA 2) chain A residue 112 type sequence A description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 3) chain A residue 113 type sequence W description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 4) chain A residue 114 type sequence N description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 5) chain A residue 140 type sequence E description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 6) chain A residue 141 type sequence V description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 7) chain A residue 168 type sequence G description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 8) chain A residue 169 type sequence V description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 9) chain A residue 187 type sequence G description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 10) chain A residue 191 type sequence V description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 11) chain A residue 194 type sequence I description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 12) chain A residue 289 type sequence H description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 13) chain A residue 292 type sequence R description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 14) chain A residue 333 type sequence E description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 15) chain A residue 335 type sequence F description BINDING SITE FOR RESIDUE NAD A 600 source : AC1 16) chain A residue 178 type MOD_RES sequence E description N6-acetyllysine => ECO:0000250|UniProtKB:P30838 source Swiss-Prot : SWS_FT_FI4 17) chain A residue 194 type MOD_RES sequence I description N6-acetyllysine => ECO:0000250|UniProtKB:P30838 source Swiss-Prot : SWS_FT_FI4 18) chain A residue 188 type BINDING sequence S description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 19) chain A residue 2 type MOD_RES sequence S description N-acetylserine => ECO:0000250|UniProtKB:P30838 source Swiss-Prot : SWS_FT_FI3 20) chain A residue 236-247 type prosite sequence FMNSGQTCVAPD description ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. FmNSGQTCVAPD source prosite : PS00070 21) chain A residue 208-215 type prosite sequence LELGGKSP description ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. LELGGKSP source prosite : PS00687 22) chain A residue 210 type ACT_SITE sequence L description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 23) chain A residue 244 type ACT_SITE sequence V description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI1

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