eF-site ID 1acm-C PDB Code 1acm Chain C click to enlarge Title ARGININE 54 IN THE ACTIVE SITE OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE IS CRITICAL FOR CATALYSIS: A SITE-SPECIFIC MUTAGENESIS, NMR AND X-RAY CRYSTALLOGRAPHY STUDY Classification TRANSFERASE (CARBAMOYL-P,ASPARTATE) Compound ASPARTATE CARBAMOYLTRANSFERASE, CATALYTIC CHAIN Source null (PYRI_ECOLI) Sequence C:  ANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLK HKVIASCFFEASTATRLSFQTSMHRLGASVVGFSDSANTS LGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSG NVPVLNAGDGSNQHPTQTLLDLFTIQQTEGRLDNLHVAMV GDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPEYILD MLDEKGIAWSLHSSIEEVMAEVDILYMTRVQKERLDPSEY ANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKT PHAWYFQQAGNGIFARQALLALVLNRDLVL Description Functional site 1) chain C residue 52 type sequence S description PAL BINDING SITES OF CHAINS C source : PAC 2) chain C residue 54 type sequence A description PAL BINDING SITES OF CHAINS C source : PAC 3) chain C residue 55 type sequence T description PAL BINDING SITES OF CHAINS C source : PAC 4) chain C residue 80 type sequence S description PAL BINDING SITES OF CHAINS C source : PAC 5) chain C residue 84 type sequence K description PAL BINDING SITES OF CHAINS C source : PAC 6) chain C residue 134 type sequence H description PAL BINDING SITES OF CHAINS C source : PAC 7) chain C residue 167 type sequence R description PAL BINDING SITES OF CHAINS C source : PAC 8) chain C residue 229 type sequence R description PAL BINDING SITES OF CHAINS C source : PAC 9) chain C residue 231 type sequence Q description PAL BINDING SITES OF CHAINS C source : PAC 10) chain C residue 52 type sequence S description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 11) chain C residue 53 type sequence T description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 12) chain C residue 54 type sequence A description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 13) chain C residue 55 type sequence T description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 14) chain C residue 80 type sequence S description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 15) chain C residue 84 type sequence K description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 16) chain C residue 105 type sequence R description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 17) chain C residue 134 type sequence H description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 18) chain C residue 167 type sequence R description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 19) chain C residue 229 type sequence R description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 20) chain C residue 231 type sequence Q description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 21) chain C residue 267 type sequence L description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 22) chain C residue 268 type sequence P description BINDING SITE FOR RESIDUE PAL C 311 source : AC4 23) chain C residue 55 type catalytic sequence T description 405 source MCSA : MCSA2 24) chain C residue 56 type catalytic sequence R description 405 source MCSA : MCSA2 25) chain C residue 85 type catalytic sequence G description 405 source MCSA : MCSA2 26) chain C residue 106 type catalytic sequence H description 405 source MCSA : MCSA2 27) chain C residue 135 type catalytic sequence P description 405 source MCSA : MCSA2 28) chain C residue 106 type BINDING sequence H description source Swiss-Prot : SWS_FT_FI1 29) chain C residue 135 type BINDING sequence P description source Swiss-Prot : SWS_FT_FI1 30) chain C residue 138 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI1 31) chain C residue 268 type BINDING sequence P description source Swiss-Prot : SWS_FT_FI1 32) chain C residue 269 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI1 33) chain C residue 56 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI1 34) chain C residue 85 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_00001, ECO:0000305|PubMed:3380787 source Swiss-Prot : SWS_FT_FI2 35) chain C residue 168 type BINDING sequence T description BINDING => ECO:0000255|HAMAP-Rule:MF_00001, ECO:0000305|PubMed:3380787 source Swiss-Prot : SWS_FT_FI2 36) chain C residue 230 type BINDING sequence V description BINDING => ECO:0000255|HAMAP-Rule:MF_00001, ECO:0000305|PubMed:3380787 source Swiss-Prot : SWS_FT_FI2

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