eF-site ID 1a94-E PDB Code 1a94 Chain E click to enlarge Title STRUCTURAL BASIS FOR SPECIFICITY OF RETROVIRAL PROTEASES Classification HYDROLASE/HYDROLASE INHIBITOR Compound PROTEASE Source Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) (POL_HV1BR) Sequence E:  PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPG RWEPKMIGGIGGFIKVRQYDQIIIEIAGHKAIGTVLVGPT PVNIIGRNLLTQIGATLNF Description Functional site 1) chain E residue 6 type sequence W description BINDING SITE FOR RESIDUE 0Q4 A 100 source : AC1 2) chain E residue 25 type sequence D description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 3) chain E residue 27 type sequence G description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 4) chain E residue 28 type sequence A description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 5) chain E residue 29 type sequence D description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 6) chain E residue 30 type sequence D description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 7) chain E residue 45 type sequence K description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 8) chain E residue 46 type sequence M description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 9) chain E residue 47 type sequence I description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 10) chain E residue 48 type sequence G description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 11) chain E residue 49 type sequence G description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 12) chain E residue 50 type sequence I description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 13) chain E residue 53 type sequence F description BINDING SITE FOR RESIDUE 0Q4 E 100 source : AC2 14) chain E residue 64 type SITE sequence I description Cleavage; by viral protease => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 15) chain E residue 64 type MOD_RES sequence I description Phosphotyrosine; by host => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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