|
eF-site ID
|
1a6a-A |
PDB Code
|
1a6a |
Chain
|
A |
|
click to enlarge
|
|
Title
|
THE STRUCTURE OF AN INTERMEDIATE IN CLASS II MHC MATURATION: CLIP BOUND TO HLA-DR3 |
Classification
|
COMPLEX (TRANSMEMBRANE/GLYCOPROTEIN) |
Compound
|
HLA class II histocompatibility antigen, DR alpha chain |
Source
|
ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; |
|
Sequence
|
A: |
HVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWR
LEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITN
VPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRN
GKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCR
VEHWGLDEPLLKHWEF
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
52 |
type |
BINDING |
sequence |
A
|
description |
BINDING => ECO:0000269|PubMed:8145819
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
2)
|
chain |
A |
residue |
55 |
type |
SITE |
sequence |
E
|
description |
Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX
|
source |
Swiss-Prot : SWS_FT_FI5
|
|
3)
|
chain |
A |
residue |
62 |
type |
SITE |
sequence |
N
|
description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX
|
source |
Swiss-Prot : SWS_FT_FI6
|
|
4)
|
chain |
A |
residue |
69 |
type |
SITE |
sequence |
N
|
description |
Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
|
source |
Swiss-Prot : SWS_FT_FI7
|
|
5)
|
chain |
A |
residue |
76 |
type |
SITE |
sequence |
R
|
description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
|
source |
Swiss-Prot : SWS_FT_FI8
|
|
6)
|
chain |
A |
residue |
78 |
type |
CARBOHYD |
sequence |
N
|
description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
|
source |
Swiss-Prot : SWS_FT_FI9
|
|
7)
|
chain |
A |
residue |
118 |
type |
CARBOHYD |
sequence |
N
|
description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
|
source |
Swiss-Prot : SWS_FT_FI9
|
|
8)
|
chain |
A |
residue |
53 |
type |
SITE |
sequence |
S
|
description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819
|
source |
Swiss-Prot : SWS_FT_FI4
|
|
9)
|
chain |
A |
residue |
161-167 |
type |
prosite |
sequence |
YDCRVEH
|
description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCQVEH
|
source |
prosite : PS00290
|
|
|
|