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|
eF-site ID
|
1a3a-A |
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PDB Code
|
1a3a |
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Chain
|
A |
|
click to enlarge
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Title
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CRYSTAL STRUCTURE OF IIA MANNITOL FROM ESCHERICHIA COLI |
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Classification
|
PHOSPHOTRANSFERASE |
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Compound
|
MANNITOL-SPECIFIC EII |
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Source
|
Escherichia coli (strain K12) (PTM3C_ECOLI) |
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Sequence
|
A: |
LFKLGAENIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYV
QAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKTGVVFCQ
YPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALD
DESVIERLAHTTSVDEVLELLAGRK
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Description
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Functional site
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|
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1)
|
chain |
A |
| residue |
65 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Tele-phosphohistidine intermediate; for EIIA activity => ECO:0000255|PROSITE-ProRule:PRU00417, ECO:0000305|PubMed:12202490, ECO:0000305|PubMed:16443929, ECO:0000305|PubMed:9551558
|
| source |
Swiss-Prot : SWS_FT_FI1
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2)
|
chain |
A |
| residue |
49 |
| type |
SITE |
| sequence |
R
|
| description |
Stabilizes the transition state in the phosphoryl transfer from HPr to EIIA => ECO:0000269|PubMed:9551558
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| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
A |
| residue |
65 |
| type |
MOD_RES |
| sequence |
H
|
| description |
Phosphohistidine; by HPr => ECO:0000269|PubMed:3142516, ECO:0000305|PubMed:12202490, ECO:0000305|PubMed:16443929, ECO:0000305|PubMed:2407724, ECO:0000305|PubMed:9551558
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
A |
| residue |
50-66 |
| type |
prosite |
| sequence |
EKLTPTYLGESIAVPHG
|
| description |
PTS_EIIA_TYPE_2_HIS PTS EIIA domains phosphorylation site signature 2. EkltptyLGesIAVPHG
|
| source |
prosite : PS00372
|
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