eF-site ID 1a2w-AB PDB Code 1a2w Chain A, B click to enlarge Title CRYSTAL STRUCTURE OF A 3D DOMAIN-SWAPPED DIMER OF BOVINE PANCREATIC RIBONUCLEASE A Classification ENDONUCLEASE Compound RIBONUCLEASE A Source ORGANISM_COMMON: cattle; ORGANISM_SCIENTIFIC: Bos taurus; Sequence A:  KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRC KPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMS ITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHF DASV B:  KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRC KPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMS ITDCRETGSSKYPNCAYKTTQANKHIIVACEGNPYVPVHF DASV Description Functional site 1) chain B residue 12 type sequence H description THE ACTIVE SITE CONTAINS RESIDUES FROM DIFFERENT SUBUNITS. source : AVE 2) chain A residue 41 type sequence K description THE ACTIVE SITE CONTAINS RESIDUES FROM DIFFERENT SUBUNITS. source : AVE 3) chain A residue 119 type sequence H description THE ACTIVE SITE CONTAINS RESIDUES FROM DIFFERENT SUBUNITS. source : AVE 4) chain A residue 119 type sequence H description BINDING SITE FOR RESIDUE CL A 501 source : AC1 5) chain B residue 12 type sequence H description BINDING SITE FOR RESIDUE CL A 501 source : AC1 6) chain A residue 33 type sequence R description BINDING SITE FOR RESIDUE CL B 502 source : AC2 7) chain B residue 39 type sequence R description BINDING SITE FOR RESIDUE CL B 502 source : AC2 8) chain A residue 11 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 601 source : AC3 9) chain A residue 12 type sequence H description BINDING SITE FOR RESIDUE SO4 B 601 source : AC3 10) chain B residue 41 type sequence K description BINDING SITE FOR RESIDUE SO4 B 601 source : AC3 11) chain B residue 119 type sequence H description BINDING SITE FOR RESIDUE SO4 B 601 source : AC3 12) chain B residue 120 type sequence F description BINDING SITE FOR RESIDUE SO4 B 601 source : AC3 13) chain A residue 12 type catalytic sequence H description 164 source MCSA : MCSA1 14) chain A residue 41 type catalytic sequence K description 164 source MCSA : MCSA1 15) chain A residue 119 type catalytic sequence H description 164 source MCSA : MCSA1 16) chain A residue 120 type catalytic sequence F description 164 source MCSA : MCSA1 17) chain A residue 121 type catalytic sequence D description 164 source MCSA : MCSA1 18) chain B residue 12 type catalytic sequence H description 164 source MCSA : MCSA2 19) chain B residue 41 type catalytic sequence K description 164 source MCSA : MCSA2 20) chain B residue 119 type catalytic sequence H description 164 source MCSA : MCSA2 21) chain B residue 120 type catalytic sequence F description 164 source MCSA : MCSA2 22) chain B residue 121 type catalytic sequence D description 164 source MCSA : MCSA2 23) chain A residue 40-46 type prosite sequence CKPVNTF description RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKpvNTF source prosite : PS00127 24) chain A residue 12 type ACT_SITE sequence H description Proton acceptor source Swiss-Prot : SWS_FT_FI1 25) chain B residue 12 type ACT_SITE sequence H description Proton acceptor source Swiss-Prot : SWS_FT_FI1 26) chain A residue 119 type ACT_SITE sequence H description Proton donor source Swiss-Prot : SWS_FT_FI2 27) chain B residue 119 type ACT_SITE sequence H description Proton donor source Swiss-Prot : SWS_FT_FI2 28) chain A residue 7 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3 29) chain B residue 85 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 30) chain A residue 10 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 31) chain A residue 41 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3 32) chain A residue 66 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3 33) chain A residue 85 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 34) chain B residue 7 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3 35) chain B residue 10 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI3 36) chain B residue 41 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3 37) chain B residue 66 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3 38) chain A residue 1 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI4 39) chain A residue 7 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI4 40) chain A residue 37 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI4 41) chain A residue 41 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI4 42) chain B residue 1 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI4 43) chain B residue 7 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI4 44) chain B residue 37 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI4 45) chain B residue 41 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI4 46) chain A residue 34 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine; partial => ECO:0000269|PubMed:19358553 source Swiss-Prot : SWS_FT_FI5 47) chain B residue 34 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine; partial => ECO:0000269|PubMed:19358553 source Swiss-Prot : SWS_FT_FI5

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