eF-site ID 1a2n-A PDB Code 1a2n Chain A click to enlarge Title STRUCTURE OF THE C115A MUTANT OF MURA COMPLEXED WITH THE FLUORINATED ANALOG OF THE REACTION TETRAHEDRAL INTERMEDIATE Classification TRANSFERASE Compound UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE Source (MURA_ECOLI) Sequence A:  MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVE IQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVF CAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGATIGAR PVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLIT LGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLV AAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWI SLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGT GFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKL SGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYE RIEDKLRALGANIERVKG Description Functional site 1) chain A residue 22 type sequence K description BINDING SITE FOR RESIDUE TET A 420 source : AC1 2) chain A residue 23 type sequence N description BINDING SITE FOR RESIDUE TET A 420 source : AC1 3) chain A residue 91 type sequence R description BINDING SITE FOR RESIDUE TET A 420 source : AC1 4) chain A residue 95 type sequence W description BINDING SITE FOR RESIDUE TET A 420 source : AC1 5) chain A residue 120 type sequence R description BINDING SITE FOR RESIDUE TET A 420 source : AC1 6) chain A residue 121 type sequence P description BINDING SITE FOR RESIDUE TET A 420 source : AC1 7) chain A residue 122 type sequence V description BINDING SITE FOR RESIDUE TET A 420 source : AC1 8) chain A residue 123 type sequence D description BINDING SITE FOR RESIDUE TET A 420 source : AC1 9) chain A residue 124 type sequence L description BINDING SITE FOR RESIDUE TET A 420 source : AC1 10) chain A residue 125 type sequence H description BINDING SITE FOR RESIDUE TET A 420 source : AC1 11) chain A residue 162 type sequence S description BINDING SITE FOR RESIDUE TET A 420 source : AC1 12) chain A residue 163 type sequence V description BINDING SITE FOR RESIDUE TET A 420 source : AC1 13) chain A residue 164 type sequence G description BINDING SITE FOR RESIDUE TET A 420 source : AC1 14) chain A residue 304 type sequence T description BINDING SITE FOR RESIDUE TET A 420 source : AC1 15) chain A residue 305 type sequence D description BINDING SITE FOR RESIDUE TET A 420 source : AC1 16) chain A residue 327 type sequence V description BINDING SITE FOR RESIDUE TET A 420 source : AC1 17) chain A residue 328 type sequence F description BINDING SITE FOR RESIDUE TET A 420 source : AC1 18) chain A residue 331 type sequence R description BINDING SITE FOR RESIDUE TET A 420 source : AC1 19) chain A residue 370 type sequence L description BINDING SITE FOR RESIDUE TET A 420 source : AC1 20) chain A residue 371 type sequence R description BINDING SITE FOR RESIDUE TET A 420 source : AC1 21) chain A residue 397 type sequence R description BINDING SITE FOR RESIDUE TET A 420 source : AC1 22) chain A residue 115 type MOD_RES sequence A description 2-(S-cysteinyl)pyruvic acid O-phosphothioketal => ECO:0000305|PubMed:22378791 source Swiss-Prot : SWS_FT_FI5 23) chain A residue 115 type ACT_SITE sequence A description Proton donor => ECO:0000269|PubMed:20392080, ECO:0000269|PubMed:8994972, ECO:0000305|PubMed:22378791, ECO:0007744|PDB:1UAE, ECO:0007744|PDB:3KR6 source Swiss-Prot : SWS_FT_FI1 24) chain A residue 22 type BINDING sequence K description BINDING => ECO:0000305|PubMed:20392080, ECO:0000305|PubMed:22378791, ECO:0007744|PDB:3KR6, ECO:0007744|PDB:3SWD source Swiss-Prot : SWS_FT_FI2 25) chain A residue 91 type BINDING sequence R description BINDING => ECO:0000269|PubMed:20392080, ECO:0007744|PDB:3KR6 source Swiss-Prot : SWS_FT_FI3 26) chain A residue 327 type BINDING sequence V description BINDING => ECO:0000269|PubMed:20392080, ECO:0007744|PDB:3KR6 source Swiss-Prot : SWS_FT_FI3 27) chain A residue 120 type BINDING sequence R description BINDING => ECO:0000269|PubMed:20392080, ECO:0000269|PubMed:22378791, ECO:0007744|PDB:3KR6 source Swiss-Prot : SWS_FT_FI4 28) chain A residue 160 type BINDING sequence K description BINDING => ECO:0000269|PubMed:20392080, ECO:0000269|PubMed:22378791, ECO:0007744|PDB:3KR6 source Swiss-Prot : SWS_FT_FI4 29) chain A residue 305 type BINDING sequence D description BINDING => ECO:0000269|PubMed:20392080, ECO:0000269|PubMed:22378791, ECO:0007744|PDB:3KR6 source Swiss-Prot : SWS_FT_FI4

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