eF-site ID 1a25-AB PDB Code 1a25 Chain A, B click to enlarge Title C2 DOMAIN FROM PROTEIN KINASE C (BETA) Classification CALCIUM-BINDING PROTEIN Compound PROTEIN KINASE C (BETA) Source null (KPCB_RAT) Sequence A:  ERRGRIYIQAHIDREVLIVVVRDAKNLVPMDPNGLSDPYV KLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDK DRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFK LLSQEEGEYFNV B:  ERRGRIYIQAHIDREVLIVVVRDAKNLVPMDPNGLSDPYV KLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDK DRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFK LLSQEEGEYFNV Description Functional site 1) chain A residue 186 type sequence M description CA BINDING SITE. source : CLB 2) chain A residue 187 type sequence D description CA BINDING SITE. source : CLB 3) chain A residue 193 type sequence D description CA BINDING SITE. source : CLB 4) chain A residue 247 type sequence W description CA BINDING SITE. source : CLB 5) chain A residue 246 type sequence D description CA BINDING SITE. source : CLB 6) chain A residue 248 type sequence D description CA BINDING SITE. source : CLB 7) chain A residue 253 type sequence N description CA BINDING SITE. source : CLB 8) chain A residue 254 type sequence D description CA BINDING SITE. source : CLB 9) chain B residue 281 type sequence E description CA BINDING SITE. source : CLB 10) chain A residue 187 type sequence D description BINDING SITE FOR RESIDUE CA A 290 source : AC1 11) chain A residue 193 type sequence D description BINDING SITE FOR RESIDUE CA A 290 source : AC1 12) chain A residue 246 type sequence D description BINDING SITE FOR RESIDUE CA A 290 source : AC1 13) chain A residue 247 type sequence W description BINDING SITE FOR RESIDUE CA A 290 source : AC1 14) chain A residue 248 type sequence D description BINDING SITE FOR RESIDUE CA A 290 source : AC1 15) chain A residue 186 type sequence M description BINDING SITE FOR RESIDUE CA A 291 source : AC2 16) chain A residue 187 type sequence D description BINDING SITE FOR RESIDUE CA A 291 source : AC2 17) chain A residue 246 type sequence D description BINDING SITE FOR RESIDUE CA A 291 source : AC2 18) chain A residue 248 type sequence D description BINDING SITE FOR RESIDUE CA A 291 source : AC2 19) chain A residue 254 type sequence D description BINDING SITE FOR RESIDUE CA A 291 source : AC2 20) chain B residue 281 type sequence E description BINDING SITE FOR RESIDUE CA A 291 source : AC2 21) chain A residue 248 type sequence D description BINDING SITE FOR RESIDUE CA A 292 source : AC3 22) chain A residue 251 type sequence S description BINDING SITE FOR RESIDUE CA A 292 source : AC3 23) chain A residue 252 type sequence R description BINDING SITE FOR RESIDUE CA A 292 source : AC3 24) chain A residue 254 type sequence D description BINDING SITE FOR RESIDUE CA A 292 source : AC3 25) chain B residue 281 type sequence E description BINDING SITE FOR RESIDUE CA A 292 source : AC3 26) chain B residue 187 type sequence D description BINDING SITE FOR RESIDUE CA B 290 source : AC4 27) chain B residue 193 type sequence D description BINDING SITE FOR RESIDUE CA B 290 source : AC4 28) chain B residue 246 type sequence D description BINDING SITE FOR RESIDUE CA B 290 source : AC4 29) chain B residue 247 type sequence W description BINDING SITE FOR RESIDUE CA B 290 source : AC4 30) chain B residue 248 type sequence D description BINDING SITE FOR RESIDUE CA B 290 source : AC4 31) chain A residue 281 type sequence E description BINDING SITE FOR RESIDUE CA B 291 source : AC5 32) chain B residue 186 type sequence M description BINDING SITE FOR RESIDUE CA B 291 source : AC5 33) chain B residue 187 type sequence D description BINDING SITE FOR RESIDUE CA B 291 source : AC5 34) chain B residue 246 type sequence D description BINDING SITE FOR RESIDUE CA B 291 source : AC5 35) chain B residue 248 type sequence D description BINDING SITE FOR RESIDUE CA B 291 source : AC5 36) chain B residue 254 type sequence D description BINDING SITE FOR RESIDUE CA B 291 source : AC5 37) chain A residue 281 type sequence E description BINDING SITE FOR RESIDUE CA B 292 source : AC6 38) chain B residue 248 type sequence D description BINDING SITE FOR RESIDUE CA B 292 source : AC6 39) chain B residue 251 type sequence S description BINDING SITE FOR RESIDUE CA B 292 source : AC6 40) chain B residue 252 type sequence R description BINDING SITE FOR RESIDUE CA B 292 source : AC6 41) chain B residue 254 type sequence D description BINDING SITE FOR RESIDUE CA B 292 source : AC6 42) chain B residue 195 type sequence Y description BINDING SITE FOR RESIDUE PSE B 1 source : AC7 43) chain B residue 197 type sequence K description BINDING SITE FOR RESIDUE PSE B 1 source : AC7 44) chain B residue 209 type sequence K description BINDING SITE FOR RESIDUE PSE B 1 source : AC7 45) chain B residue 211 type sequence K description BINDING SITE FOR RESIDUE PSE B 1 source : AC7 46) chain B residue 245 type sequence W description BINDING SITE FOR RESIDUE PSE B 1 source : AC7 47) chain B residue 253 type sequence N description BINDING SITE FOR RESIDUE PSE B 1 source : AC7 48) chain A residue 186 type BINDING sequence M description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 49) chain A residue 187 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 50) chain B residue 186 type BINDING sequence M description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 51) chain B residue 187 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 52) chain B residue 193 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 53) chain B residue 246 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 54) chain B residue 247 type BINDING sequence W description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 55) chain B residue 248 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 56) chain B residue 251 type BINDING sequence S description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 57) chain B residue 252 type BINDING sequence R description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 58) chain B residue 254 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 59) chain A residue 193 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 60) chain A residue 246 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 61) chain A residue 247 type BINDING sequence W description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 62) chain A residue 248 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 63) chain A residue 251 type BINDING sequence S description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 64) chain A residue 252 type BINDING sequence R description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 65) chain A residue 254 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21215369, ECO:0000269|PubMed:9817842 source Swiss-Prot : SWS_FT_FI1 66) chain A residue 206 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P05771 source Swiss-Prot : SWS_FT_FI2 67) chain B residue 206 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P05771 source Swiss-Prot : SWS_FT_FI2 68) chain A residue 250 type MOD_RES sequence T description Phosphothreonine; by autocatalysis => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 69) chain B residue 250 type MOD_RES sequence T description Phosphothreonine; by autocatalysis => ECO:0000250 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links