eF-site ID 1a1j-ABC
PDB Code 1a1j
Chain A, B, C

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Title RADR (ZIF268 VARIANT) ZINC FINGER-DNA COMPLEX (GCGT SITE)
Classification TRANSCRIPTION/DNA
Compound DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*GP*T)-3')
Source (1A1J)
Sequence A:  RPYACPVESCDRRFSRSADLTRHIRIHTGQKPFQCRICMR
NFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHT
KIHL
B:  AGCGTGGGCGT
C:  TACGCCCACGC
Description


Functional site

1) chain A
residue 107
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 201
source : AC1

2) chain A
residue 112
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 201
source : AC1

3) chain A
residue 125
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 201
source : AC1

4) chain A
residue 129
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 201
source : AC1

5) chain A
residue 137
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 202
source : AC2

6) chain A
residue 140
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 202
source : AC2

7) chain A
residue 153
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 202
source : AC2

8) chain A
residue 157
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 202
source : AC2

9) chain A
residue 165
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 203
source : AC3

10) chain A
residue 168
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 203
source : AC3

11) chain A
residue 181
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 203
source : AC3

12) chain A
residue 185
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 203
source : AC3

13) chain A
residue 107-129
type prosite
sequence CPVESCDRRFSRSADLTRHIRIH
description ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CpvesCdrrFsrsadltrHiri..H
source prosite : PS00028

14) chain A
residue 137-157
type prosite
sequence CRICMRNFSRSDHLTTHIRTH
description ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CpvesCdrrFsrsadltrHiri..H
source prosite : PS00028

15) chain A
residue 165-185
type prosite
sequence CDICGRKFARSDERKRHTKIH
description ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CpvesCdrrFsrsadltrHiri..H
source prosite : PS00028

16) chain A
residue 130-154
type ZN_FING
sequence TGQKPFQCRICMRNFSRSDHLTTHI
description C2H2-type 1 => ECO:0000255|PROSITE-ProRule:PRU00042
source Swiss-Prot : SWS_FT_FI1

17) chain A
residue 160-182
type ZN_FING
sequence EKPFACDICGRKFARSDERKRHT
description C2H2-type 2 => ECO:0000255|PROSITE-ProRule:PRU00042
source Swiss-Prot : SWS_FT_FI2

18) chain A
residue 128
type SITE
sequence I
description Interaction with DNA => ECO:0000269|PubMed:2028256, ECO:0000269|PubMed:8939742, ECO:0007744|PDB:1AAY, ECO:0007744|PDB:1ZAA
source Swiss-Prot : SWS_FT_FI3

19) chain A
residue 139
type SITE
sequence I
description Interaction with DNA => ECO:0000269|PubMed:2028256, ECO:0000269|PubMed:8939742, ECO:0007744|PDB:1AAY, ECO:0007744|PDB:1ZAA
source Swiss-Prot : SWS_FT_FI3

20) chain A
residue 143
type SITE
sequence N
description Interaction with DNA => ECO:0000269|PubMed:2028256, ECO:0000269|PubMed:8939742, ECO:0007744|PDB:1AAY, ECO:0007744|PDB:1ZAA
source Swiss-Prot : SWS_FT_FI3

21) chain A
residue 149
type SITE
sequence H
description Interaction with DNA => ECO:0000269|PubMed:2028256, ECO:0000269|PubMed:8939742, ECO:0007744|PDB:1AAY, ECO:0007744|PDB:1ZAA
source Swiss-Prot : SWS_FT_FI3

22) chain A
residue 167
type SITE
sequence I
description Interaction with DNA => ECO:0000269|PubMed:2028256, ECO:0000269|PubMed:8939742, ECO:0007744|PDB:1AAY, ECO:0007744|PDB:1ZAA
source Swiss-Prot : SWS_FT_FI3

23) chain A
residue 171
type SITE
sequence K
description Interaction with DNA => ECO:0000269|PubMed:2028256, ECO:0000269|PubMed:8939742, ECO:0007744|PDB:1AAY, ECO:0007744|PDB:1ZAA
source Swiss-Prot : SWS_FT_FI3


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