eF-site ID 1a12-ABC PDB Code 1a12 Chain A, B, C click to enlarge Title REGULATOR OF CHROMOSOME CONDENSATION (RCC1) OF HUMAN Classification GUANINE NUCLEOTIDE EXCHANGE FACTOR Compound REGULATOR OF CHROMOSOME CONDENSATION 1 Source (RCC1_HUMAN) Sequence A:  KKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKP ALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALG RDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRV FLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASG NDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL ERLLVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGH VYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS GGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTL ISRLPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTG QDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQ S B:  KKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKP ALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALG RDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRV FLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASG NDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL ERLLVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGH VYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS GGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTL ISRLPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTG QDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQ S C:  KKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKP ALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALG RDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRV FLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASG NDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGL ERLLVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGH VYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFS GGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTL ISRLPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTG QDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQ S Description Functional site 1) chain A residue 92-103 type prosite sequence GCNDEGALGRDT description RCC1_1 Regulator of chromosome condensation (RCC1) signature 1. GcNDegALGRdT source prosite : PS00625 2) chain A residue 124-134 type prosite sequence VSAGDSHTAAL description RCC1_2 Regulator of chromosome condensation (RCC1) signature 2. VSAGdSHTAAL source prosite : PS00626 3) chain A residue 177-187 type prosite sequence VASGNDHLVML description RCC1_2 Regulator of chromosome condensation (RCC1) signature 2. VSAGdSHTAAL source prosite : PS00626 4) chain A residue 299-309 type prosite sequence FSGGQHHTVCM description RCC1_2 Regulator of chromosome condensation (RCC1) signature 2. VSAGdSHTAAL source prosite : PS00626 5) chain A residue 404-414 type prosite sequence VSSGGQHTVLL description RCC1_2 Regulator of chromosome condensation (RCC1) signature 2. VSAGdSHTAAL source prosite : PS00626

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