eF-site ID 1a0j-A PDB Code 1a0j Chain A click to enlarge Title CRYSTAL STRUCTURE OF A NON-PSYCHROPHILIC TRYPSIN FROM A COLD-ADAPTED FISH SPECIES. Classification SERINE PROTEASE Compound TRYPSIN Source ORGANISM_COMMON: Atlantic salmon; ORGANISM_SCIENTIFIC: Salmo salar; Sequence A:  IVGGYECRKNSASYQASLQSGYHFCGGSLISSTWVVSAAH CYKSRIQVRLGEHNIAVNEGTEQFIDSVKVIMHPSYNSRN LDNDIMLIKLSKPASLNSYVSTVALPSSCASSGTRCLVSG WGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNM FCAGFMEGGKDSCQGDSGGPVVCNGQLQGVVSWGYGCAQR NKPGVYTKVCNYRSWISSTMSSN Description Functional site 1) chain A residue 70 type sequence E description BINDING SITE FOR RESIDUE CA A 247 source : AC1 2) chain A residue 72 type sequence N description BINDING SITE FOR RESIDUE CA A 247 source : AC1 3) chain A residue 75 type sequence V description BINDING SITE FOR RESIDUE CA A 247 source : AC1 4) chain A residue 77 type sequence E description BINDING SITE FOR RESIDUE CA A 247 source : AC1 5) chain A residue 80 type sequence E description BINDING SITE FOR RESIDUE CA A 247 source : AC1 6) chain A residue 40 type sequence H description BINDING SITE FOR RESIDUE SO4 A 248 source : AC2 7) chain A residue 57 type sequence H description BINDING SITE FOR RESIDUE SO4 A 248 source : AC2 8) chain A residue 192 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 248 source : AC2 9) chain A residue 193 type sequence G description BINDING SITE FOR RESIDUE SO4 A 248 source : AC2 10) chain A residue 195 type sequence S description BINDING SITE FOR RESIDUE SO4 A 248 source : AC2 11) chain A residue 152 type sequence P description BINDING SITE FOR RESIDUE SO4 A 249 source : AC3 12) chain A residue 153 type sequence D description BINDING SITE FOR RESIDUE SO4 A 249 source : AC3 13) chain A residue 154 type sequence T description BINDING SITE FOR RESIDUE SO4 A 249 source : AC3 14) chain A residue 156 type sequence R description BINDING SITE FOR RESIDUE SO4 A 249 source : AC3 15) chain A residue 39 type sequence Y description BINDING SITE FOR RESIDUE SO4 D 248 source : AC8 16) chain A residue 76 type sequence N description BINDING SITE FOR RESIDUE SO4 D 249 source : AC9 17) chain A residue 148 type sequence S description BINDING SITE FOR RESIDUE SO4 D 250 source : BC1 18) chain A residue 149 type sequence S description BINDING SITE FOR RESIDUE SO4 D 250 source : BC1 19) chain A residue 189 type sequence D description BINDING SITE FOR RESIDUE BEN A 246 source : BC3 20) chain A residue 190 type sequence S description BINDING SITE FOR RESIDUE BEN A 246 source : BC3 21) chain A residue 195 type sequence S description BINDING SITE FOR RESIDUE BEN A 246 source : BC3 22) chain A residue 219 type sequence G description BINDING SITE FOR RESIDUE BEN A 246 source : BC3 23) chain A residue 220 type sequence C description BINDING SITE FOR RESIDUE BEN A 246 source : BC3 24) chain A residue 226 type sequence G description BINDING SITE FOR RESIDUE BEN A 246 source : BC3 25) chain A residue 53-58 type prosite sequence VSAAHC description TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC source prosite : PS00134 26) chain A residue 189-200 type prosite sequence DSCQGDSGGPVV description TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV source prosite : PS00135 27) chain A residue 57 type ACT_SITE sequence H description Charge relay system => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 28) chain A residue 102 type ACT_SITE sequence D description Charge relay system => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 29) chain A residue 195 type ACT_SITE sequence S description Charge relay system => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 30) chain A residue 70 type BINDING sequence E description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 31) chain A residue 72 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 32) chain A residue 80 type BINDING sequence E description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 33) chain A residue 75 type BINDING sequence V description source Swiss-Prot : SWS_FT_FI3 34) chain A residue 189 type SITE sequence D description Required for specificity => ECO:0000250 source Swiss-Prot : SWS_FT_FI4

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