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eF-site ID
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1a02-ABFJN |
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PDB Code
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1a02 |
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Chain
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A, B, F, J, N |
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click to enlarge
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Title
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STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA |
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Classification
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TRANSCRIPTION/DNA |
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Compound
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DNA (5'-D(*DTP*DTP*DGP*DGP*DAP*DAP*DAP*DAP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DCP*DAP*DTP*DAP*DG)-3') |
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Source
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null (1A02) |
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Sequence
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A: |
TTGGAAAATTTGTTTCATAG
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| B: |
AACTATGAAACAAATTTTCC
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| F: |
RRIRRERNKMAAAKSRNRRRELTDTLQAETDQLEDEKSAL
QTEIANLLKEKEK
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| J: |
RKRMRNRIAASKSRKRKLERIARLEEKVKTLKAQNSELAS
TANMLREQVAQL
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| N: |
WPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTG
GHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHR
ITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGI
LKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIV
SLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMIL
TGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNML
FVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPV
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Description
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Functional site
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1)
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chain |
J |
| residue |
267-282 |
| type |
prosite |
| sequence |
RKRMRNRIAASKSRKR
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| description |
BZIP_BASIC Basic-leucine zipper (bZIP) domain signature. Rre.RNKmAAAKsRNR
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| source |
prosite : PS00036
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|
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2)
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chain |
F |
| residue |
143-157 |
| type |
prosite |
| sequence |
RRERNKMAAAKSRNR
|
| description |
BZIP_BASIC Basic-leucine zipper (bZIP) domain signature. Rre.RNKmAAAKsRNR
|
| source |
prosite : PS00036
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3)
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chain |
J |
| residue |
281 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0000269|PubMed:11689449
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| source |
Swiss-Prot : SWS_FT_FI2
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4)
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chain |
J |
| residue |
296 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine; by PAK2 => ECO:0000269|PubMed:21177766
|
| source |
Swiss-Prot : SWS_FT_FI3
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5)
|
chain |
J |
| residue |
282 |
| type |
SITE |
| sequence |
R
|
| description |
Necessary for synergistic transcriptional activity with SMAD3
|
| source |
Swiss-Prot : SWS_FT_FI1
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